Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728802 | 0.94 | PDGFRB (0.45) | PDGFRBKDM4EMAPTMAPK1 | |
| SCHEMBL4583394 | 0.92 | MEN1 (0.53) | KDM4EMAPTMAPK1 | |
| SCHEMBL4582316 | 0.92 | GAA (0.53) | KDM4EMAPTMAPK1 | |
| SCHEMBL4581838 | 0.90 | KDM4E (0.49) | KDM4EMAPTMAPK1 | |
| SCHEMBL4583297 | 0.86 | GAA (0.61) | PDGFRB | |
| SCHEMBL4582512 | 0.86 | MEN1 (0.53) | PDGFRB | |
| SCHEMBL4583852 | 0.86 | PDGFRB (0.49) | PDGFRB | |
| SCHEMBL4726676 | 0.84 | KDM4E (0.45) | KDM4EMAPTMAPK1 | |
| SCHEMBL4582297 | 0.84 | MAPT (0.47) | PDGFRBMAPT | |
| SCHEMBL4727134 | 0.83 | GAA (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080125435-A1 | 1-(Het)aryl-3-[hetaryl-piperidin-4-yl]-thioureas as modulators of the EP2 receptor | BAYER SCHERING PHARMA AG (DE) | 2008-05-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125435-A1 | 1-(Het)aryl-3-[hetaryl-piperidin-4-yl]-thioureas as modulators of the EP2 receptor | PTGER2, PTGER1, PTGES2 | PDGFRB 129/4885KDM4E 4022/4885MAPT 4796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.