Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4912166 | 0.94 | PDGFRB (0.50) | PDGFRBKDM4EMAPTMAPK1 | |
| SCHEMBL4582316 | 0.87 | GAA (0.53) | KDM4EMAPTMAPK1 | |
| SCHEMBL4583189 | 0.87 | ADRB2 (0.47) | — | |
| SCHEMBL4583394 | 0.87 | MEN1 (0.53) | KDM4EMAPTMAPK1 | |
| SCHEMBL4728602 | 0.86 | PAK1 (0.44) | PDGFRB | |
| SCHEMBL4581838 | 0.84 | KDM4E (0.49) | KDM4EMAPTMAPK1 | |
| SCHEMBL4583162 | 0.81 | ADRB2 (0.49) | — | |
| SCHEMBL4583297 | 0.81 | GAA (0.61) | PDGFRB | |
| SCHEMBL4582512 | 0.81 | MEN1 (0.53) | PDGFRB | |
| SCHEMBL4583852 | 0.81 | PDGFRB (0.49) | PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008028690-A1 | 1-(HET)ARYL-3-[HETARYL-PIPERIDIN-4-YL]-THIOUREAS AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | disclosed |