⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402757 | 0.82 | — | — | |
| SCHEMBL8628582 | 0.80 | — | — | |
| SCHEMBL8995533 | 0.78 | TSHR (0.44) | — | |
| SCHEMBL10527279 | 0.78 | TSHR (0.44) | — | |
| SCHEMBL491153 | 0.75 | — | — | |
| SCHEMBL1019544 | 0.75 | — | — | |
| SCHEMBL294559 | 0.73 | — | — | |
| SCHEMBL12646872 | 0.73 | — | — | |
| SCHEMBL11203655 | 0.73 | — | — | |
| SCHEMBL585309 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110230478-A1 | 4-Alkyl-substituted diaminopyrimidines | Bayer ScienceCrop AG (DE) | 2011-09-22 | — | — | US | claimed |
| EP-2330904-A2 | 4-ALKYL-SUBSTITUTED DIAMINOPYRIMIDINES | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | claimed |
| WO-2010025863-A2 | 4-ALKYL-SUBSTITUTED DIAMINOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | claimed |
| US-4360375-A | Phenoxyphenoxy unsaturated derivatives and herbicidal composition | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1982-11-23 | — | — | US | claimed |
| US-20140018377-A1 | Aminopropenoates as Fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-16 | — | — | US | disclosed |
| US-8476197-B2 | Aminopropenoates as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-07-02 | — | — | US | disclosed |
| US-8106194-B2 | Pyrrolopyrimidine and pyrrolotriazine derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-01-31 | — | — | US | disclosed |
| US-20110230478-A1 | 4-Alkyl-substituted diaminopyrimidines | Bayer ScienceCrop AG (DE) | 2011-09-22 | — | — | US | disclosed |
| US-20110152322-A1 | Aminopropenoates as Fungicides | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
| EP-2330904-A2 | 4-ALKYL-SUBSTITUTED DIAMINOPYRIMIDINES | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| US-20110137031-A1 | PYRROLOPYRIMIDINE AND PYRROLOTRIAZINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-06-09 | — | — | US | disclosed |
| CN-1910185-B | Pyrrolopyrimidine and pyrrolotriazine derivatives as CRF receptor antagonists | TAISHO PHARMACEUTICAL CO LTD | 2010-05-26 | — | — | CN | disclosed |
| EP-1706410-A2 | PYRROLOPYRIMIDINE AND PYRROLOTRIAZINE DERIVATIVES AS CRF RECEPTOR ANTAGONISTS | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005085253-A1 | PYRROLOPYRIMIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2005-09-15 | — | — | WO | disclosed |
| WO-2005066142-A2 | PYRROLOPYRIMIDINE AND PYRROLOTRIAZINE DERIVATIVES AS CRF RECEPTOR ANTAGONISTS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2005-07-21 | — | — | WO | disclosed |
| EP-0882051-A1 | THIOPHENOPYRIMIDINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1998-12-09 | — | — | EP | disclosed |
| WO-1997029110-A1 | THIOPHENOPYRIMIDINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-08-14 | — | — | WO | disclosed |
| US-4894398-A | HYROXYLAMINES AS STORAGE STABILIZERS IN OXYGEN-IMPERVIOUS CONTAINERS | DOW CORNING CORPORATION (US) | 1990-01-16 | — | — | US | disclosed |
| US-4360375-A | Phenoxyphenoxy unsaturated derivatives and herbicidal composition | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1982-11-23 | — | — | US | disclosed |
| US-4263040-A | Phenoxyphenoxy unsaturated derivatives and herbicidal composition | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1981-04-21 | — | — | US | disclosed |