⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491153 | 0.81 | — | — | |
| SCHEMBL11620532 | 0.74 | — | — | |
| SCHEMBL12817323 | 0.74 | — | — | |
| SCHEMBL618838 | 0.74 | — | — | |
| SCHEMBL12817321 | 0.74 | — | — | |
| SCHEMBL491241 | 0.73 | — | — | |
| SCHEMBL9292615 | 0.72 | PTGS1 (0.37) | — | |
| SCHEMBL433669 | 0.71 | — | — | |
| SCHEMBL895317 | 0.71 | — | — | |
| SCHEMBL9402757 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 570 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10766899-B2 | Methods for preparing substituted imidazo[4,5-b]pyrazines | CYTOKINETICS, INCORPORATED (US) | 2020-09-08 | — | — | US | claimed |
| EP-2995619-B1 | CERTAIN CHEMICAL ENTITIES COMPRISING IMIDAZOPYRIMIDINES, COMPOSITIONS AND METHODS | CYTOKINETICS INC (US) | 2019-09-25 | — | — | EP | claimed |
| US-20190284148-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-19 | — | — | US | claimed |
| CN-108341902-A | Catalytic component for vinyl polymerization and preparation method thereof and catalyst for vinyl polymerization | 中国石油化工股份有限公司 | 2018-07-31 | — | — | CN | claimed |
| CN-108341901-A | Catalytic component for vinyl polymerization and preparation method thereof and catalyst for vinyl polymerization | 中国石油化工股份有限公司 | 2018-07-31 | — | — | CN | claimed |
| US-20170266192-A1 | METHODS FOR IMPROVING DIAPHRAGM FUNCTION | CYTOKINETICS INC (US) | 2017-09-21 | — | — | US | claimed |
| EP-2545055-B1 | Imidazo[1,2-a]pyrazine derivatives and their use for the prevention or treatment of neurological, psychiatric and metabolic disorders and diseases | JANSSEN PHARMACEUTICA NV (BE) | 2017-08-09 | — | — | EP | claimed |
| EP-2069352-B9 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | CYTOKINETICS INC (US) | 2017-03-15 | — | — | EP | claimed |
| EP-2995619-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS COMPRISING IMIDAZOPYRIMIDINES | Cytokinetics, Inc. (US) | 2016-03-16 | — | — | EP | claimed |
| US-20160052964-A1 | METHODS AND COMPOSITIONS USING ADAM10 INHIBITORS TO TREAT BACTERIAL INFECTIONS | THE UNIVERSITY OF CHICAGO (US) | 2016-02-25 | — | — | US | claimed |
| WO-2001040193-A1 | METHOD FOR THE SYNTHESIS OF PYRAZOLINES | CHEMRX ADVANCED TECHNOLOGIES, INC. (US) | 2001-06-07 | — | — | WO | claimed |
| EP-1090005-A1 | PYRAZOLO 1,5-a]TRIAZINE CORTICOTROPIN RELEASING FACTOR ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2001-04-11 | — | — | EP | claimed |
| WO-1999067247-A1 | PYRAZOLO[1,5-a]TRIAZINE CORTICOTROPIN RELEASING FACTOR ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-12-29 | — | — | WO | claimed |
| EP-0074511-B1 | 2H-1,2,4,6-THIATRIAZIN(3)ON-1,1 DIOXIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BASF Aktiengesellschaft (DE) | 1987-12-09 | — | — | EP | claimed |
| US-4659722-A | NONPHYTOTOXIC | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1987-04-21 | — | — | US | claimed |
| US-4593090-A | Containing perhydrofuran or pyran ring structure | GOGO KIMURA (JP) | 1986-06-03 | — | — | US | claimed |
| EP-0172545-A1 | 3-or 4-pyridinecarboxamide-derivates and their use as bactericides | NIPPON KAYAKU CO., LTD. (JP) | 1986-02-26 | — | — | EP | claimed |
| EP-0039426-B1 | THIATRIAZINE DIOXIDES AND HERBICIDAL COMPOSITIONS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1984-01-18 | — | — | EP | claimed |
| US-4316015-A | 6H-1,2,4,6-Thiatriazine-1,1-dioxides | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-16 | — | — | US | claimed |
| US-4240822-A | HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1980-12-23 | — | — | US | claimed |