Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Albuterol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 10/20 | 1.00 |
| ▸ | ADRB1 | P08588 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.97 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Albuterol SCHEMBL2489838 | 1.00 | ADRB2 (1.00) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| Albuterol SCHEMBL10025126 | 1.00 | ADRB2 (1.00) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| (S)-Albuterol SCHEMBL5881204 | 1.00 | ADRB2 (1.00) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| Levosalbutamol SCHEMBL4003 | 1.00 | ADRB2 (1.00) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| Albuterol SCHEMBL121596 | 1.00 | ADRB2 (1.00) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| Albuterol SCHEMBL122805 | 1.00 | ADRB2 (1.00) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| Levosalbutamol SCHEMBL29361075 | 1.00 | ADRB2 (1.00) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| (S)-Albuterol SCHEMBL29496690 | 1.00 | ADRB2 (1.00) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| Albuterol SCHEMBL28434340 | 0.98 | ADRB2 (0.97) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| Levosalbutamol SCHEMBL29620266 | 0.98 | TDP1 (1.00) | ADRB2ADRB1CYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 75358 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423298-B1 | — | — | None | — | — | US | claimed |
| EP-4747263-A1 | LIPID NANOPARTICLES AND USES THEREOF | University of Connecticut (US) | 2026-05-27 | — | — | EP | claimed |
| CN-122094963-A | Cardioprotective lipids and methods of use | — | 2026-05-26 | — | — | CN | claimed |
| CN-122071418-A | Preparation method of salbutamol sulfate, salbutamol sulfate injection and preparation method of salbutamol sulfate injection | 海南皇隆制药股份有限公司 | 2026-05-22 | — | — | CN | claimed |
| WO-2026106917-A1 | EDIBLE TRANSMUCOSAL DRUG DELIVERY METHOD USING AN INTERMEDIATE CAPSULE AS A TEMPORARY VESSEL | BioPhysics Pharma, Inc. (US) | 2026-05-21 | — | — | WO | claimed |
| US-20260139860-A1 | PRODUCTS OF MANUFACTURE FOR THE TREATMENT, PREVENTION AND AMELIORATION OF MICROBIAL INFECTIONS | CENTRE FOR DIGESTIVE DISEASES (AU) | 2026-05-21 | — | — | US | claimed |
| EP-4743371-A1 | DEVICE FOR DISPENSING A FLUID PRODUCT | APTAR France SAS (FR) | 2026-05-20 | — | — | EP | claimed |
| EP-4743063-A1 | SALBUTAMOL DELIVERY FORMULATIONS, DEVICES AND METHODS | Solstice Advanced Materials US, Inc. (US) | 2026-05-20 | — | — | EP | claimed |
| CN-224247570-U | Salbutamol fluorescence quantitative determination card | 北京普赞生物技术有限公司 | 2026-05-15 | — | — | CN | claimed |
| WO-2026098941-A1 | NEBULISER SYSTEMS | Acu-Flow Limited (GB) | 2026-05-15 | — | — | WO | claimed |
| EP-0046144-A1 | Therapeutically active derivatives of phenylethanol amines | Aktiebolaget Draco (SE) | 1982-02-17 | — | — | EP | claimed |
| EP-0043807-A2 | 1-(Dihydroxyphenyl)-2-amino-ethanol derivatives; preparation, compositions and intermediates | Aktiebolaget Draco (SE) | 1982-01-13 | — | — | EP | claimed |
| EP-0036426-A1 | NOVEL PROCESS AND INTERMEDIATES USEFUL IN THE PREPARATION OF SYMPATHOMIMETIC AMINES. | INTERX RESEARCH CORP (US) | 1981-09-30 | — | — | EP | claimed |
| US-4275219-A | Novel process and intermediates useful in the preparation of sympathomimetic amines | INTERX RESEARCH CORPORATION (US) | 1981-06-23 | — | — | US | claimed |
| WO-1981000849-A1 | NOVEL PROCESS AND INTERMEDIATES USEFUL IN THE PREPARATION OF SYMPATHOMIMETIC AMINES | INTERX RESEARCH CORP (US) | 1981-04-02 | — | — | WO | claimed |
| US-4199578-A | TREATMENT OF ASTHMA OR HAY FEVER | FISONS LIMITED (GB) | 1980-04-22 | — | — | US | claimed |
| US-4153677-A | MICROENCAPSULATED BRONCHODILATOR AGENT, ETHYL CELLULOSE FILM | STERLING DRUG INC. (US) | 1979-05-08 | — | — | US | claimed |
| US-4147767-A | CROSSLINKED WITH FORMALDEHYDE OR GLUTARALDEHYDE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1979-04-03 | — | — | US | claimed |
| US-4034087-A | TREATING PROLIFERATIVE SKIN DISEASES WITH 4-BENZYL-2-IMIDAZOLIDONES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1977-07-05 | — | — | US | claimed |
| US-3981398-A | Aid in the management of clinical emergencies in medical and dental practices and other circumstances | Pienaar, Hendrik Lukas (ZA) | 1976-09-21 | — | — | US | claimed |