Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 18/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14087089 | 1.00 | KCNH2 (0.65) | KCNH2 | |
| SCHEMBL4916311 | 0.88 | KCNH2 (0.80) | KCNH2 | |
| SCHEMBL14087077 | 0.88 | KCNH2 (0.80) | KCNH2 | |
| SCHEMBL3272571 | 0.87 | KCNH2 (0.62) | KCNH2 | |
| SCHEMBL3273036 | 0.87 | KCNH2 (0.62) | KCNH2 | |
| SCHEMBL3277787 | 0.87 | KCNH2 (0.62) | KCNH2 | |
| SCHEMBL3277534 | 0.86 | KCNH2 (0.63) | KCNH2 | |
| SCHEMBL3278931 | 0.86 | KCNH2 (0.63) | KCNH2 | |
| SCHEMBL5429897 | 0.85 | KCNH2 (0.61) | KCNH2 | |
| SCHEMBL3281264 | 0.80 | KCNH2 (0.77) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194547-A1 | Antibacterial Agents | GLAXO GROUP LIMITED (GB) | 2008-08-14 | — | — | US | claimed |
| US-20080194547-A1 | Antibacterial Agents | GLAXO GROUP LIMITED (GB) | 2008-08-14 | — | — | US | disclosed |
| EP-1773847-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006010040-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2006-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194547-A1 | Antibacterial Agents | NQO2, NQO1, NDUFV2 | KCNH2 3310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.