NDUFV2 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Auraptene (SCHEMBL2535029)	1.00	5/20
Auraptene (SCHEMBL2535034)	1.00	5/20
SCHEMBL8491443	0.56	4/20
SCHEMBL8489900	0.52	4/20
SCHEMBL8489907	0.52	4/20
SCHEMBL8492838	0.52	4/20
SCHEMBL8492845	0.52	4/20
SCHEMBL8489902	0.51	4/20
SCHEMBL8489908	0.51	4/20
SCHEMBL8491154	0.51	4/20
SCHEMBL8491160	0.51	4/20
SCHEMBL8491619	0.50	4/20
SCHEMBL8491624	0.50	4/20
SCHEMBL8491634	0.50	4/20
SCHEMBL8494171	0.50	4/20
SCHEMBL8494175	0.50	4/20
SCHEMBL8494177	0.50	4/20
7-Prenyloxycoumarin (SCHEMBL4898255)	0.79	3/20
SCHEMBL712741	0.57	3/20
Geiparvarin (SCHEMBL2532495)	0.56	3/20

Clinical trials — most relevant to NDUFV2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Phase III Trial of Coenzyme Q10 in Mitochondrial Disease	PHASE3	COMPLETED
A Study of the Efficacy and Safety of MT1621 in Thymidine Kinase 2 (TK2) Deficiency (Treatment naïve)	PHASE3	WITHDRAWN
Coenzyme Q10 as a Symptomatic Treatment in Parkinson's Disease	PHASE3	COMPLETED
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder	PHASE2	WITHDRAWN
Trial of Nicotinamide Riboside and Co-enzyme Q10 in Chronic Kidney Disease	PHASE2	COMPLETED
Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease	PHASE2	RECRUITING
A Study to Evaluate Vitamin B3 Derivative to Treat Mitochondrial Myopathy	PHASE2	ACTIVE_NOT_RECRUITING
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome	PHASE1/PHASE2	COMPLETED
Does Clinical Treatment of Mitochondrial Dysfunction Impact Autism Spectrum Disorder (ASD)?	PHASE1	UNKNOWN
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine	nan	COMPLETED
Evaluation of Impact of Disease and Visual Disability on Quality of Life and Loss of Independence of Patients Living in France With Leber's Hereditary Optic Neuropathy (LHON) Through Qualitative and Quantitative Data Collection	nan	COMPLETED
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	nan	RECRUITING
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
MITOMICS : a Multi-OMICS Approach for the Diagnosis of Mitochondrial Diseases	nan	RECRUITING
The Natural History of Mitochondrial Diseases	nan	RECRUITING
Identification of Large-Scale Mutations of POLG Gene by QMPSF in Patients With Mitochondrial DNA Instability.	nan	UNKNOWN
Nicotinamide Riboside and Mitochondrial Biogenesis	nan	COMPLETED
GDF-15 as a Biomarker for Mitochondrial Disease	nan	COMPLETED
Natural History in Primary Mitochondrial Myopathies	nan	RECRUITING
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip	nan	COMPLETED
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes	nan	NOT_YET_RECRUITING
Survey on Supplement Use in Mitochondrial Disease	nan	COMPLETED
The Genetics of Diabetes in Southern California Chinese Americans	nan	WITHDRAWN
Safety and Efficacy Study of rAAV2-ND4 Treatment of Leber Hereditary Optic Neuropathy (LHON)	nan	COMPLETED
Ccf mtDNA as a Neurodegenerative Biomarker	nan	UNKNOWN
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants	nan	RECRUITING
Cardiac Mitochondrial Function in Explanted Human Hearts	nan	UNKNOWN
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular Powerhouse) Dysfunction	nan	COMPLETED
Mitoquines in COPD	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a NDUFV2 binder may also engage these)

Protein	Name	Similarity
Q0MQI9	—	1.000	Q0MQI9 →
P04394	—	1.000	P04394 →
Q0MQI7	—	1.000	Q0MQI7 →
Q0MQI8	—	1.000	Q0MQI8 →
Q9D6J6	—	0.999	Q9D6J6 →
P19234	—	0.997	P19234 →
Q20719	—	0.996	Q20719 →
P40915	—	0.995	P40915 →
Q54F10	—	0.982	Q54F10 →
O22769	—	0.979	O22769 →
P29914	—	0.971	P29914 →
Q11190	—	0.968	Q11190 →
P22944	—	0.964	P22944 →
Q4K8L6	—	0.964	Q4K8L6 →
SPTLC3	Serine palmitoyltransferase 3	0.964	landscape →
O23813	—	0.964	O23813 →
P46643	—	0.963	P46643 →
Q8IQF1	—	0.963	Q8IQF1 →
A9UZ24	—	0.962	A9UZ24 →
P45575	—	0.962	P45575 →
P94694	—	0.962	P94694 →
Q02252	—	0.962	Q02252 →
Q43644	—	0.962	Q43644 →
GOT2	Aspartate aminotransferase, mitochondrial	0.962	landscape →
Q9V7Y2	—	0.962	Q9V7Y2 →
A7SDA8	—	0.962	A7SDA8 →
Q5REB0	—	0.961	Q5REB0 →
Q54XM6	—	0.961	Q54XM6 →
Q4UM09	—	0.961	Q4UM09 →
O04630	—	0.961	O04630 →