Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 15/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CCL5 | P13501 | 2/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4909355 | 0.90 | CCR5 (0.74) | CCR5KCNH2CYP2D6CYP3A4 | |
| SCHEMBL4912506 | 0.89 | CCR5 (0.64) | CCR5KCNH2CYP2D6CYP3A4CCL5 | |
| SCHEMBL4910561 | 0.89 | CCR5 (0.65) | CCR5KCNH2CYP2D6CYP3A4CCL5 | |
| SCHEMBL4915650 | 0.88 | CCR5 (0.64) | CCR5KCNH2CYP2D6CYP3A4CCL5 | |
| SCHEMBL4913842 | 0.87 | CCR5 (0.63) | CCR5KCNH2CYP2D6CYP3A4CCL5 | |
| SCHEMBL4911584 | 0.87 | CCR5 (0.60) | CCR5KCNH2CYP2D6CYP3A4CCL5 | |
| SCHEMBL4915469 | 0.87 | CCR5 (0.72) | CCR5KCNH2CYP2D6CYP3A4 | |
| SCHEMBL4912473 | 0.86 | CCR5 (0.62) | CCR5KCNH2CYP2D6CYP3A4CCL5 | |
| SCHEMBL4915550 | 0.86 | CCR5 (0.70) | CCR5KCNH2CYP2D6CYP3A4 | |
| SCHEMBL4915712 | 0.86 | CCR5 (0.68) | CCR5KCNH2CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200460-A1 | Chemical Compounds | BROWN DEARG | 2008-08-21 | — | — | US | disclosed |
| US-20080200460-A1 | Chemical Compounds | BROWN DEARG | 2008-08-21 | — | — | US | disclosed |
| US-20080200460-A1 | Chemical Compounds | BROWN DEARG | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200460-A1 | Chemical Compounds | CCR5, CXCR4, CXCR5 | CCR5 1/4885KCNH2 2817/4885CYP2D6 198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.