Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 20/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 10/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 10/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4914750 | 1.00 | CHRM3 (0.55) | CHRM3CHRM2CHRM1 | |
| Bromide SCHEMBL3819169 | 0.77 | CHRM3 (0.66) | CHRM3CHRM2CHRM1 | |
| Bromide SCHEMBL4912091 | 0.77 | CHRM3 (0.66) | CHRM3CHRM2CHRM1 | |
| SCHEMBL3818588 | 0.76 | CHRM3 (0.64) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4254213 | 0.75 | CHRM3 (0.66) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4912920 | 0.74 | CHRM3 (0.62) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4165130 | 0.74 | CHRM3 (0.63) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4912924 | 0.74 | CHRM3 (0.62) | CHRM3CHRM2CHRM1 | |
| SCHEMBL5438579 | 0.74 | CHRM3 (0.63) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4910584 | 0.72 | CHRM3 (0.64) | CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275079-A1 | 3-Endo)-3-[2,2-Bis-(3-hydroxy-phenyl)-ethenyl]-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide; chronic obstructive lung disease, chronic bronchitis, asthma, chronic respiratory obstruction, pulmonary fibrosis, pulmonary emphysema, allergic rhinitis | GLAXO GROUP LIMITED | 2008-11-06 | — | — | US | disclosed |
| US-20080234315-A1 | M3 Muscarinic Acetylcholine Receptor Antagonists | GLAXO GROUP LIMITED (GB) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234315-A1 | M3 Muscarinic Acetylcholine Receptor Antagonists | CHRM3, CHRM2, CHRM1 | CHRM3 1/4885CHRM2 2/4885CHRM1 3/4885 |
| US-20080275079-A1 | 3-Endo)-3-[2,2-Bis-(3-hydroxy-phenyl)-ethenyl]-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide; chronic obstructive lung disease, chronic bronchitis, asthma, chronic respiratory obstruction, pulmonary fibrosis, pulmonary emphysema, allergic rhinitis | CHRM3, EDNRB, BDKRB2 | CHRM3 1/4885CHRM2 7/4885CHRM1 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.