SCHEMBL491489

SCHEMBL491489

C=C(C)C(=O)Nc1ccc(CP(=O)(OCC)OCC)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.47
NPY5R Q15761 1/20 0.45
FGFR1 P11362 1/20 0.42
FGFR4 P22455 1/20 0.42
BTK Q06187 2/20 0.41
PTK2 Q05397 2/20 0.41
SRC P12931 1/20 0.40
HDAC1 Q13547 1/20 0.40
ENTPD2 Q9Y5L3 1/20 0.39
ENPP2 Q13822 1/20 0.39
DGAT2 Q96PD7 1/20 0.39
TDP1 Q9NUW8 2/20 0.39
CCNT1 O60563 2/20 0.39
CDK9 P50750 2/20 0.39
ENTPD1 P49961 1/20 0.38
MAPT P10636 1/20 0.38
EGFR P00533 1/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1486740 0.85 KMT2A (0.53) NPY5RSRCTDP1MAPTMEN1
SCHEMBL5277253 0.84 NPY5R (0.43) NPY5RBTKPTK2SRCHDAC1
SCHEMBL19331999 0.82 NPY5R (0.48) NPY5RBTKPTK2SRCHDAC1
SCHEMBL13714950 0.81 NPY5R (0.44) NPY5RBTKPTK2SRCHDAC1
SCHEMBL21052528 0.81 ENPP2 (0.54) RXFP1FGFR1FGFR4SRCENPP2
SCHEMBL491746 0.81 BTK (0.57) NPY5RBTKPTK2LMNA
SCHEMBL3024941 0.79 ENPP2 (0.46) NPY5RHDAC1ENTPD2ENPP2DGAT2
Hydrochloric Acid SCHEMBL3024939 0.78 ENPP2 (0.45) NPY5RHDAC1ENTPD2ENPP2DGAT2
SCHEMBL5280572 0.78 ENPP2 (0.45) NPY5RBTKSRCHDAC1ENTPD2
SCHEMBL13802232 0.77 RXFP1 (0.59) RXFP1FGFR1FGFR4SRCHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8105689-B2 Adhesive, coating or film composition applied to a surface BASF SE (DE) 2012-01-31 US disclosed
US-8105689-B2 Adhesive, coating or film composition applied to a surface BASF SE (DE) 2012-01-31 US disclosed
US-8105689-B2 Adhesive, coating or film composition applied to a surface BASF SE (DE) 2012-01-31 US disclosed
EP-1902078-B1 (METH)ACRYLAMIDE PHOSPHORUS MONOMER COMPOSITION BASF SE (DE) 2011-06-22 EP disclosed
EP-1902078-A1 (METH)ACRYLAMIDE PHOSPHORUS MONOMER COMPOSITION Ciba Specialty Chemicals Holding, Inc. (CH) 2008-03-26 EP disclosed
US-20070028805-A1 (Meth)acrylamide phosphorus monomer compositions BASF SE (DE) 2007-02-08 US disclosed
US-20070028805-A1 (Meth)acrylamide phosphorus monomer compositions BASF SE (DE) 2007-02-08 US disclosed
US-20070028805-A1 (Meth)acrylamide phosphorus monomer compositions BASF SE (DE) 2007-02-08 US disclosed
WO-2007006648-A1 (METH)ACRYLAMIDE PHOSPHORUS MONOMER COMPOSITION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-01-18 WO disclosed
WO-2007006648-A1 (METH)ACRYLAMIDE PHOSPHORUS MONOMER COMPOSITION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-01-18 WO disclosed