Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4916547 | 0.98 | TSHR (0.57) | TSHRTHRBHTTPOLBAPEX1 | |
| SCHEMBL4918092 | 0.95 | TSHR (0.51) | TSHRTHRBHTTPOLBAPEX1 | |
| SCHEMBL16425936 | 0.95 | TSHR (0.51) | TSHRTHRBHTTPOLBAPEX1 | |
| SCHEMBL24099523 | 0.93 | TSHR (0.50) | TSHRTHRBHTTPOLBAPEX1 | |
| SCHEMBL16309297 | 0.92 | TSHR (0.53) | TSHRTHRBHTTPOLBAPEX1 | |
| SCHEMBL16309307 | 0.90 | THRB (0.48) | TSHRTHRBHTTPOLBAPEX1 | |
| SCHEMBL17830827 | 0.89 | TSHR (0.63) | TSHRFAAHLPAR1LPAR2ENPP2 | |
| SCHEMBL16309329 | 0.88 | TSHR (0.58) | TSHRTHRBHTTPOLBAPEX1 | |
| SCHEMBL4917590 | 0.88 | THRB (0.47) | TSHRTHRBHTTPOLBAPEX1 | |
| SCHEMBL22939772 | 0.88 | TSHR (0.49) | TSHRTHRBHTTPOLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2578200-A1 | Compounds for infiltrating and/or sealing of dental hard substance and method | VOCO GmbH (DE) | 2013-04-10 | — | — | EP | disclosed |
| US-20080102262-A1 | Radiation Curable Composition and Curing Product Thereof, and Laminate Including the Same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2008-05-01 | — | — | US | disclosed |