SCHEMBL491558

SCHEMBL491558

Clc1[c]c(Cl)cc(Br)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL491394 0.85
SCHEMBL1637718 0.81
SCHEMBL698051 0.75 NT5E (0.30)
SCHEMBL17514676 0.74
SCHEMBL58386 0.72
SCHEMBL457802 0.71
SCHEMBL4579025 0.71
SCHEMBL634867 0.67
SCHEMBL5514481 0.67
Benzene SCHEMBL8015363 0.67 TSHR (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023073222-A1 INHIBITORS OF VIRAL HELICASES BINDING TO A NOVEL ALLOSTERIC BINDING SITE EISBACH BIO GMBH (DE) 2023-05-04 WO claimed
CN-114213353-A Aryl-oxazole-oxazoline compound and preparation method and application thereof 贵州大学 2022-03-22 CN claimed
US-8435978-B2 Substituted sulfonamide compounds GRUENENTHAL GMBH (DE) 2013-05-07 US claimed
EP-1648886-B1 BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS ESTEVE LABOR DR (ES) 2009-12-09 EP claimed
US-20070032482-A1 Benzoxazinone-derived sulfonamide compounds, their preparation and use as medicaments LABORATORIOS DEL DR. ESTEVE S.A. (ES) 2007-02-08 US claimed
CN-1860114-A Benzoxazinone-derived sulfonamide compounds, process for their preparation and their use as pharmaceuticals ESTEVE LABOR DR (ES) 2006-11-08 CN claimed
EP-1648886-A1 BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2006-04-26 EP claimed
WO-2005014589-A1 BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS LABORATORIOS DEL DR. ESTEVE S.A. (DE) 2005-02-17 WO claimed
US-20020016468-A1 PESTICIDAL 1-ARYLPYRAZOLE DERIVATIVES RHONE-POULENC AGROCHIMIE (FR) 2002-02-07 US claimed
EP-0511845-B1 Pesticidal 1-aryl-5-(substituted alkylideneimino)-pyrazoles AVENTIS CROPSCIENCE SA (FR) 2001-10-31 EP claimed
EP-0839809-A1 Pesticidal 1-arylpyrazole-5-sulfinilimine derivatives RHONE-POULENC AGROCHIMIE (FR) 1998-05-06 EP claimed
US-5691333-A APPLYING TO CONTROL ARTHROPODS AND NEMATODES RHONE-POULENC INC. (US) 1997-11-25 US claimed
US-5629335-A Pesticidal 1-arylpyrazole-3-carboximidothioic acid esters RHONE-POULENC INC. (US) 1997-05-13 US claimed
US-5556873-A AGRICULTURAL PESTICIDES RHONE-POULENC INC. (US) 1996-09-17 US claimed
US-5321040-A Pesticidal 1-aryl-5-(substituted N-cinnamylideneimino) pyrazoles RHONE-POULENC INC. (US) 1994-06-14 US claimed
US-5236938-A Pesticidal 1-aryl-5-(substituted alkylideneimino)pyrazoles RHONE-POULENC INC. (US) 1993-08-17 US claimed
EP-0511845-A1 Pesticidal 1-aryl-5-(substituted alkylideneimino)-pyrazoles RHONE-POULENC AGROCHIMIE (FR) 1992-11-04 EP claimed
EP-0007986-B1 SUBSTITUTED 2-PHENYLAMINO-IMIDAZOLINES-(2), THEIR ACID ADDITION SALTS, MEDICAMENTS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION C.H. BOEHRINGER SOHN (DE) 1981-09-16 EP claimed
US-4239764-A FOR SLOWING HEART RATE BOEHRINGER INGELHEIM GMBH (DE) 1980-12-16 US claimed
US-4212779-A Cathodically depositable binders VIANOVA KUNSTHARZ, A.G. (AT) 1980-07-15 US claimed