Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 8/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4920011 | 0.95 | TSHR (0.46) | TSHRACHEEPHX1DGKACES2 | |
| SCHEMBL515795 | 0.89 | TSHR (0.38) | TSHRACHEEPHX1CES2CES1 | |
| Dimethylamine SCHEMBL27916692 | 0.86 | TSHR (0.46) | TSHRACHEEPHX1DGKACES2 | |
| SCHEMBL170886 | 0.85 | TSHR (0.52) | TSHRACHEEPHX1DGKACES2 | |
| SCHEMBL5167857 | 0.83 | TSHR (0.60) | TSHRACHEEPHX1DGKACES2 | |
| SCHEMBL3081526 | 0.83 | TSHR (0.55) | TSHRACHEEPHX1DGKACES2 | |
| SCHEMBL3477341 | 0.83 | TSHR (0.50) | TSHRACHEDGKACES2CES1 | |
| SCHEMBL515811 | 0.83 | TSHR (0.43) | TSHRACHEEPHX1ALDH1A1HPGD | |
| SCHEMBL29094305 | 0.82 | THRB (0.32) | TSHRACHETHRB | |
| SCHEMBL29168696 | 0.82 | TSHR (0.53) | TSHRACHEEPHX1DGKACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080057434-A1 | METHOD OF PRODUCING NON-MAGNETIC ONE-COMPONENT TONER FOR DEVELOPING ELECTROSTATIC IMAGE | ZEON CORPORATION (JP) | 2008-03-06 | — | — | US | disclosed |
| US-4163092-A | QUATERNIZED MONOMER, CROSS-LINKING AGENT | PLASTOMEDICAL SCIENCES, INC. (US) | 1979-07-31 | — | — | US | disclosed |
| US-4060678-A | Cationic hydrogels based on hydroxyalkyl acrylates and methacrylates | PLASTOMEDICAL SCIENCES, INC. (US) | 1977-11-29 | — | — | US | disclosed |
| US-4058491-A | Cationic hydrogels based on heterocyclic N-vinyl monomers | PLASTOMEDICAL SCIENCES, INC. (US) | 1977-11-15 | — | — | US | disclosed |