⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL954499 | 0.97 | CXCR3 (0.42) | — | |
| SCHEMBL8184252 | 0.97 | CXCR3 (0.42) | — | |
| SCHEMBL8184253 | 0.97 | CXCR3 (0.42) | — | |
| SCHEMBL954500 | 0.97 | CXCR3 (0.42) | — | |
| SCHEMBL8185904 | 0.97 | CXCR3 (0.42) | — | |
| SCHEMBL199976 | 0.97 | — | — | |
| SCHEMBL8185902 | 0.97 | CXCR3 (0.42) | — | |
| SCHEMBL8184432 | 0.97 | CXCR3 (0.42) | — | |
| SCHEMBL8184430 | 0.97 | CXCR3 (0.42) | — | |
| SCHEMBL73140 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2860 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11535751-B2 | Asymmetrically substituted polyorganosiloxane derivatives | MOMENTIVE PERFORMANCE MATERIALS GMBH | 2022-12-27 | — | — | US | claimed |
| WO-2022256299-A1 | 7-MORPHOLINO-5-(3-PHENYL-1 H-PYRAZOL-1 -YL)-FURO[3,2-B]PYRIDINE DERIVATIVES AND SIMILAR COMPOUNDS AS PIKFYVE KINASE INHIBITORS FOR THE TREATMENT OF E.G. AMYOTROPHIC LATERAL SCLEROSIS (ALS) | Verge Analytics, Inc. (US) | 2022-12-08 | — | — | WO | claimed |
| CN-108026279-B | Asymmetrically substituted polyorganosiloxane derivatives | 莫门蒂夫性能材料有限公司 | 2022-04-01 | — | — | CN | claimed |
| CN-108026372-B | Modified filler particles and silicone compositions containing the same | 莫门蒂夫性能材料有限公司 | 2022-03-15 | — | — | CN | claimed |
| US-20180371248-A1 | ASYMMETRICALLY SUBSTITUTED POLYORGANOSILOXANE DERIVATIVES | CITIBANK, N.A., AS ADMINISTRATIVE AGENT | 2018-12-27 | — | — | US | claimed |
| US-20180208718-A1 | MODIFIED FILLER PARTICLES AND SILICONE COMPOSITIONS COMPRISING THE SAME | MOMENTIVE PERFORMANCE MATERIALS INC. | 2018-07-26 | — | — | US | claimed |
| EP-3325540-A1 | ASYMMETRICALLY SUBSTITUTED POLYORGANOSILOXANE DERIVATIVES | Momentive Performance Materials GmbH (DE) | 2018-05-30 | — | — | EP | claimed |
| EP-3325557-A1 | MODIFIED FILLER PARTICLES AND SILICONE COMPOSITIONS COMPRISING THE SAME | Momentive Performance Materials GmbH (DE) | 2018-05-30 | — | — | EP | claimed |
| CN-108026279-A | The poly organo alkane derivatives of Asymmetrical substitute | 莫门蒂夫性能材料有限公司 | 2018-05-11 | — | — | CN | claimed |
| CN-108026372-A | Modified filler particles and the silicon composition comprising the particle | 莫门蒂夫性能材料有限公司 | 2018-05-11 | — | — | CN | claimed |
| US-4923754-A | PRIMARY COATING FOR OPTICAL FIBERS | DOW CORNING CORPORATION (US) | 1990-05-08 | — | — | US | claimed |
| EP-0332991-A1 | Substituted triazoles | BAYER AG (DE) | 1989-09-20 | — | — | EP | claimed |
| EP-0157540-B1 | CURABLE ORGANOPOLYSILOXANE COMPOSITIONS | Dow Corning Limited (GB) | 1989-01-11 | — | — | EP | claimed |
| US-4780486-A | MERCAPTO CROSSLINKING | DOW CORNING CORPORATION (US) | 1988-10-25 | — | — | US | claimed |
| US-4587136-A | Curable organopolysiloxane compositions | DOW CORNING LTD. (GB) | 1986-05-06 | — | — | US | claimed |
| EP-0024960-B1 | SUBSTITUTED HETEROCYCLIC PHENOXY AMINES, THEIR PREPARATION METHOD AND THEIR USE AS LOCAL ANAESTHETICS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1984-12-12 | — | — | EP | claimed |
| US-4381310-A | Antimycotic substituted 2,4-dichlorophenyl-imidazolyl-vinyl-carbinols | BAYER AKTIENGESELLSCHAFT (DE) | 1983-04-26 | — | — | US | claimed |
| EP-0048828-A1 | Substituted 2,4-dichlorophenyl-imidazolyl-vinyl carbinols, process for their preparation and antimicrobial agents containing these compounds | BAYER AG (DE) | 1982-04-07 | — | — | EP | claimed |
| EP-0048827-A1 | Substituted 2,4-dichlorophenyl-imidazolyl-vinyl ketones, processes for their preparation and antimicrobial agents containing these compounds | BAYER AG (DE) | 1982-04-07 | — | — | EP | claimed |
| EP-0024960-A2 | Substituted heterocyclic phenoxy amines, their preparation method and their use as local anaesthetics | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1981-03-11 | — | — | EP | claimed |