Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 17/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441132 | 0.94 | DGAT1 (0.59) | DGAT1MEN1POLBKMT2A | |
| SCHEMBL441208 | 0.92 | DGAT1 (0.54) | DGAT1 | |
| SCHEMBL442538 | 0.91 | DGAT1 (0.59) | DGAT1MEN1POLBKMT2A | |
| SCHEMBL463631 | 0.91 | DGAT1 (0.58) | DGAT1 | |
| SCHEMBL440825 | 0.90 | DGAT1 (0.58) | DGAT1 | |
| SCHEMBL463723 | 0.90 | DGAT1 (0.51) | DGAT1MEN1KMT2A | |
| SCHEMBL440581 | 0.90 | DGAT1 (0.60) | DGAT1 | |
| SCHEMBL463649 | 0.89 | DGAT1 (0.52) | DGAT1 | |
| SCHEMBL441133 | 0.89 | DGAT1 (0.53) | DGAT1POLB | |
| SCHEMBL438636 | 0.89 | DGAT1 (0.58) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008011130-A2 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-24 | — | — | WO | disclosed |