Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4920970 | 0.81 | HRH3 (1.00) | HRH3SLC6A4 | |
| SCHEMBL4921779 | 0.79 | HRH3 (0.94) | HRH3SLC6A4 | |
| SCHEMBL4803006 | 0.77 | HRH3 (0.78) | HRH3SLC6A4 | |
| SCHEMBL19633495 | 0.77 | HRH3 (0.66) | HRH3SLC6A4 | |
| SCHEMBL5204296 | 0.77 | HRH3 (1.00) | HRH3SLC6A4 | |
| SCHEMBL5203533 | 0.77 | HRH3 (1.00) | HRH3SLC6A4 | |
| SCHEMBL5205287 | 0.76 | HRH3 (0.61) | HRH3SLC6A4 | |
| SCHEMBL30692542 | 0.75 | HRH3 (0.53) | HRH3SLC6A4 | |
| SCHEMBL25545457 | 0.73 | ACACB (0.45) | HRH3 | |
| SCHEMBL737003 | 0.72 | HRH3 (0.68) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139564-A1 | SUBSTITUTED PHENYL PROPYL AMINES AS HISTAMINE H3 RECEPTOR AND SEROTONIN TRANSPORTER MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139564-A1 | SUBSTITUTED PHENYL PROPYL AMINES AS HISTAMINE H3 RECEPTOR AND SEROTONIN TRANSPORTER MODULATORS | HRH3, SLC6A4, HNMT | HRH3 1/4885SLC6A4 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.