Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491653 | 0.93 | P2RX7 (0.71) | P2RX7 | |
| SCHEMBL17323959 | 0.83 | P2RX7 (0.88) | P2RX7 | |
| SCHEMBL17327671 | 0.81 | P2RX7 (0.65) | P2RX7 | |
| SCHEMBL491858 | 0.79 | P2RX7 (0.71) | P2RX7 | |
| SCHEMBL22878864 | 0.79 | P2RX7 (0.71) | P2RX7 | |
| Water SCHEMBL492139 | 0.79 | P2RX7 (0.70) | P2RX7 | |
| SCHEMBL1805240 | 0.78 | P2RX7 (0.69) | P2RX7 | |
| SCHEMBL5767624 | 0.78 | P2RX7 (0.69) | P2RX7 | |
| SCHEMBL1805331 | 0.78 | P2RX7 (0.69) | P2RX7 | |
| SCHEMBL17324044 | 0.78 | P2RX7 (0.81) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106073-B2 | Quinoline derivatives 057 | ASTRAZENECA AB (SE) | 2012-01-31 | — | — | US | disclosed |