Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.56 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4919558 | 1.00 | CYP4F2 (0.56) | CYP4F2CYP4A11USP2SMN1; SMN2NR1H2 | |
| SCHEMBL12193909 | 0.91 | CYP4F2 (0.48) | CYP4F2CYP4A11USP2SMN1; SMN2NR1H2 | |
| SCHEMBL18728345 | 0.89 | CYP4F2 (0.46) | CYP4F2CYP4A11USP2SMN1; SMN2NR1H2 | |
| SCHEMBL12194260 | 0.88 | CYP4F2 (0.47) | CYP4F2CYP4A11USP2SMN1; SMN2NR1H2 | |
| SCHEMBL4728851 | 0.87 | CYP4F2 (0.52) | CYP4F2CYP4A11USP2SMN1; SMN2NR1H2 | |
| SCHEMBL4728853 | 0.87 | CYP4F2 (0.52) | CYP4F2CYP4A11USP2SMN1; SMN2NR1H2 | |
| SCHEMBL4295685 | 0.82 | PKM (0.49) | CYP4F2CYP4A11USP2SMN1; SMN2NR1H2 | |
| SCHEMBL7303096 | 0.81 | USP2 (0.47) | CYP4F2CYP4A11USP2SMN1; SMN2NR1H2 | |
| SCHEMBL1764579 | 0.81 | CYP4F2 (0.63) | CYP4F2CYP4A11USP2SMN1; SMN2NR1H2 | |
| SCHEMBL2157135 | 0.81 | USP2 (0.51) | CYP4F2CYP4A11USP2SMN1; SMN2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051419-A1 | AMINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER INC. | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051419-A1 | AMINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | CCNY, CCND2, CCND1 | CYP4F2 2966/4885CYP4A11 3825/4885USP2 4431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.