Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.59 |
| ▸ | SLC6A9 | P48067 | 7/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733888 | 0.94 | SLC6A4 (0.65) | SLC6A4HRH3SLC6A2HTR1A | |
| Trifluoroacetic Acid SCHEMBL4919829 | 0.89 | SLC6A4 (0.64) | SLC6A4HRH3SLC6A9SLC6A2HTR1A | |
| SCHEMBL14172982 | 0.88 | SLC6A4 (0.63) | SLC6A4HRH3SLC6A9SLC6A2HTR1A | |
| SCHEMBL14172984 | 0.88 | SLC6A4 (0.63) | SLC6A4HRH3SLC6A9SLC6A2HTR1A | |
| SCHEMBL4920894 | 0.85 | SLC6A4 (0.79) | SLC6A4HRH3SLC6A2 | |
| Trifluoroacetic Acid SCHEMBL4925610 | 0.84 | SLC6A4 (0.75) | SLC6A4HRH3SLC6A9SLC6A2HTR1A | |
| Trifluoroacetic Acid SCHEMBL4919069 | 0.83 | SLC6A4 (0.60) | SLC6A4HRH3SLC6A9SLC6A2HTR1A | |
| SCHEMBL4782608 | 0.83 | SLC6A4 (0.64) | SLC6A4HRH3SLC6A2HTR1A | |
| Trifluoroacetic Acid SCHEMBL4913054 | 0.79 | SLC6A4 (0.70) | SLC6A4HRH3SLC6A9SLC6A2HTR1A | |
| SCHEMBL14173432 | 0.79 | SLC6A4 (0.77) | SLC6A4HRH3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139564-A1 | SUBSTITUTED PHENYL PROPYL AMINES AS HISTAMINE H3 RECEPTOR AND SEROTONIN TRANSPORTER MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139564-A1 | SUBSTITUTED PHENYL PROPYL AMINES AS HISTAMINE H3 RECEPTOR AND SEROTONIN TRANSPORTER MODULATORS | HRH3, SLC6A4, HNMT | SLC6A4 2/4885HRH3 1/4885SLC6A9 97/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.