Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30748852 | 0.76 | PARP1 (0.33) | PARP1NOTUMHTR1A | |
| SCHEMBL15635817 | 0.76 | PARP1 (0.33) | PARP1NOTUMHTR1A | |
| SCHEMBL25166593 | 0.76 | PARP1 (0.34) | PARP1NOTUM | |
| SCHEMBL30888596 | 0.75 | NOTUM (0.32) | PARP1NOTUM | |
| SCHEMBL31550049 | 0.73 | PARP1 (0.33) | PARP1NOTUM | |
| SCHEMBL14824890 | 0.73 | PARP1 (0.33) | PARP1NOTUMHTR1A | |
| SCHEMBL4924693 | 0.73 | HTR2A (0.32) | HTR1A | |
| SCHEMBL1142943 | 0.73 | PARP1 (0.37) | PARP1NOTUMHTR1A | |
| SCHEMBL25166676 | 0.73 | HTR2A (0.32) | HTR1A | |
| SCHEMBL1142545 | 0.72 | CTNNB1 (0.34) | PARP1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080020148-A1 | Chromane Derivatives Method for Production and the Use Thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080020148-A1 | Chromane Derivatives Method for Production and the Use Thereof | C1S, CHRM1, C1R | PARP1 4676/4885NOTUM 1634/4885HTR1A 352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.