SCHEMBL4920523

SCHEMBL4920523

COC[C@H](NC(=O)c1nn(Cc2cccc(Cl)c2)c2c1CCCCC2)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.46
PTGER4 P35408 3/20 0.42
PPARG P37231 1/20 0.41
TAS1R3 Q7RTX0 1/20 0.40
TAS1R1 Q7RTX1 1/20 0.40
MAPK1 P28482 1/20 0.39
TP53 P04637 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
MAPT P10636 1/20 0.39
POLB P06746 1/20 0.38
TACR3 P29371 1/20 0.38
AGTR1 P30556 2/20 0.38
KCNK3 O14649 1/20 0.38
CTSL P07711 1/20 0.37
MME P08473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2843685 0.79 PTGER4 (0.48) PTGER4TP53MEN1KMT2AMAPT
SCHEMBL2870198 0.79 PTGER4 (0.48) PTGER4TP53MEN1KMT2AMAPT
SCHEMBL14003140 0.78 ALDH1A1 (0.53) CNR2PTGER4MAPK1MEN1KMT2A
SCHEMBL13889613 0.78 ALDH1A1 (0.53) CNR2PTGER4MAPK1MEN1KMT2A
SCHEMBL13011093 0.75 CNR2 (0.81) CNR2TAS1R3TAS1R1MAPK1CTSL
SCHEMBL13011099 0.75 CNR2 (0.81) CNR2TAS1R3TAS1R1MAPK1CTSL
SCHEMBL14258996 0.74 CNR2 (0.82) CNR2TAS1R3TAS1R1MAPK1CTSL
SCHEMBL14258998 0.74 CNR2 (0.82) CNR2TAS1R3TAS1R1MAPK1CTSL
SCHEMBL14258995 0.74 CNR2 (0.82) CNR2TAS1R3TAS1R1MAPK1CTSL
SCHEMBL14089790 0.74 CNR2 (0.82) CNR2TAS1R3TAS1R1MAPK1CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080234347-A1 METHOD FOR TREATING CB2 RECEPTOR MEDIATED PAIN JANSSEN PHARMACEUTICA N.V. (BE) 2008-09-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080234347-A1 METHOD FOR TREATING CB2 RECEPTOR MEDIATED PAIN CNR2, CNR1, NPY4R CNR2 1/4885PTGER4 89/4885PPARG 381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.