Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30898290 | 0.86 | TSHR (0.57) | TSHRKDM4EHPGDCYP1A2CYP2C9 | |
| SCHEMBL25281274 | 0.86 | HPGD (0.66) | TSHRKDM4EHPGDCYP1A2MEN1 | |
| SCHEMBL29212238 | 0.86 | TSHR (0.57) | TSHRKDM4EHPGDCYP1A2CYP2C9 | |
| SCHEMBL5240670 | 0.81 | MAPK9 (0.48) | TSHRKDM4EHPGDCYP1A2CYP2C9 | |
| SCHEMBL23997359 | 0.80 | HPGD (0.57) | TSHRHPGDCYP1A2MEN1KMT2A | |
| SCHEMBL739521 | 0.79 | HPGD (0.62) | TSHRHPGDCYP1A2MEN1KMT2A | |
| SCHEMBL21463542 | 0.79 | HPGD (0.56) | TSHRHPGDCYP1A2MEN1KMT2A | |
| SCHEMBL7248358 | 0.78 | HPGD (0.74) | TSHRKDM4EHPGDCYP1A2MEN1 | |
| SCHEMBL23997256 | 0.74 | HPGD (0.57) | TSHRHPGDCYP1A2MEN1KMT2A | |
| SCHEMBL25275996 | 0.73 | HPGD (0.56) | TSHRHPGDCYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058376-A1 | PIPERIDINES | ICAGEN, INC. (US) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058376-A1 | PIPERIDINES | TRPV3, SCN3A, TRPV1 | TSHR 4322/4885KDM4E 2585/4885HPGD 1030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.