Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4912865 | 0.89 | HRH4 (0.43) | HRH4MAPTMEN1KMT2ALMNA | |
| SCHEMBL4912873 | 0.89 | HRH4 (0.43) | HRH4MAPTMEN1KMT2ALMNA | |
| SCHEMBL31484371 | 0.89 | HRH4 (0.58) | HRH4MAPTMEN1KMT2ALMNA | |
| SCHEMBL28773675 | 0.89 | HRH4 (0.58) | HRH4MAPTMEN1KMT2ALMNA | |
| SCHEMBL2499503 | 0.87 | MAPT (0.48) | HRH4MAPTMEN1KMT2ALMNA | |
| SCHEMBL2499501 | 0.87 | MAPT (0.48) | HRH4MAPTMEN1KMT2ALMNA | |
| SCHEMBL9618347 | 0.78 | PTPN1 (0.54) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL9618346 | 0.78 | PTPN1 (0.54) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL4920839 | 0.77 | METAP1 (0.51) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4920823 | 0.77 | METAP1 (0.51) | MAPTMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080171146-A1 | Vapor deposited electro-optic films self-assembled through hydrogen bonding | MARKS TOBIN J | 2008-07-17 | — | — | US | disclosed |
| US-7291293-B2 | Chromophore comprising pyrimidin-2,4,6-trione and/or pyrrolidinedione/2,5-/ derivative with diaminomelamine or aminopurinone groups; quality, thickness; electrooptic films; acentric microstructure | NORTHWESTERN UNIVERSITY (US) | 2007-11-06 | — | — | US | disclosed |