Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618346 | 1.00 | PTPN1 (0.54) | PTPN1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL71402 | 0.82 | PTPN1 (0.73) | PTPN1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL31301140 | 0.82 | PTPN1 (0.73) | PTPN1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL71401 | 0.82 | PTPN1 (0.73) | PTPN1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL5379059 | 0.82 | PTPN1 (0.73) | PTPN1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL2627847 | 0.82 | PTPN1 (0.73) | PTPN1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL8211756 | 0.80 | PTPN1 (0.63) | PTPN1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL19893827 | 0.80 | PTPN1 (0.63) | PTPN1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL9000578 | 0.79 | PTPN1 (0.61) | PTPN1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL9000600 | 0.79 | PTPN1 (0.61) | PTPN1ALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4300874-A | — | — | None | — | — | JP | disclosed |
| JP-H04300874-A | NEW 2,4-DIAMINO-1,3,5-TRIAZINE DERIVATIVE | TSUMURA & CO | 1992-10-23 | — | — | JP | disclosed |