Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4921089 | 0.85 | HRH3 (0.76) | HRH3SLC6A4SLC6A2 | |
| SCHEMBL4919962 | 0.84 | HRH3 (0.71) | MEN1KMT2AHRH3SLC6A4SLC6A2 | |
| SCHEMBL4919839 | 0.84 | HRH3 (0.71) | MEN1KMT2AHRH3SLC6A4SLC6A2 | |
| SCHEMBL4925845 | 0.82 | HRH3 (0.71) | MEN1KMT2AHRH3SLC6A4SLC6A2 | |
| SCHEMBL4923581 | 0.82 | HRH3 (0.74) | MEN1KMT2AHRH3SLC6A4SLC6A2 | |
| SCHEMBL4919893 | 0.80 | HRH3 (0.72) | MEN1KMT2AHRH3SLC6A4SLC6A2 | |
| SCHEMBL4919952 | 0.80 | HRH3 (0.71) | MEN1KMT2AL3MBTL1HRH3SLC6A4 | |
| SCHEMBL4923183 | 0.77 | HRH3 (0.74) | MEN1KMT2AL3MBTL1HRH3SLC6A4 | |
| SCHEMBL4918877 | 0.77 | HRH3 (0.75) | MEN1KMT2AL3MBTL1HRH3SLC6A4 | |
| Trifluoroacetic Acid SCHEMBL4920779 | 0.77 | SLC6A4 (0.67) | HRH3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139564-A1 | SUBSTITUTED PHENYL PROPYL AMINES AS HISTAMINE H3 RECEPTOR AND SEROTONIN TRANSPORTER MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139564-A1 | SUBSTITUTED PHENYL PROPYL AMINES AS HISTAMINE H3 RECEPTOR AND SEROTONIN TRANSPORTER MODULATORS | HRH3, SLC6A4, HNMT | MEN1 2363/4885KMT2A 610/4885CYP1A2 1356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.