Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL390293 | 0.76 | DPP4 (0.77) | DPP4OPRM1OPRK1 | |
| SCHEMBL390089 | 0.76 | DPP4 (0.77) | DPP4OPRM1OPRK1 | |
| SCHEMBL8234532 | 0.67 | DPP4 (0.53) | DPP4OPRM1OPRK1 | |
| SCHEMBL1458474 | 0.65 | DPP4 (0.78) | DPP4 | |
| SCHEMBL386356 | 0.65 | DPP4 (0.70) | DPP4OPRM1OPRK1 | |
| SCHEMBL386355 | 0.65 | DPP4 (0.70) | DPP4OPRM1OPRK1 | |
| SCHEMBL11908439 | 0.64 | KEAP1 (0.59) | DPP4PIM1PIM3PIM2 | |
| SCHEMBL12517572 | 0.64 | DPP4 (0.78) | DPP4 | |
| SCHEMBL13896890 | 0.63 | DPP4 (0.77) | DPP4 | |
| SCHEMBL386733 | 0.63 | DPP4 (1.00) | DPP4OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108808-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | FENG JUN | 2008-05-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108808-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | DPP4, DPP3, DPP9 | DPP4 1/4885MAPK1 4356/4885PIM1 1308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.