Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 17/20 | 0.76 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.76 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.53 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734353 | 0.89 | SLC6A4 (0.76) | HRH3SLC6A4SLC6A2LTA4HCACNA1B | |
| SCHEMBL4920955 | 0.87 | HRH3 (0.74) | HRH3SLC6A4SLC6A2 | |
| SCHEMBL4922124 | 0.87 | SLC6A4 (1.00) | HRH3SLC6A4SLC6A2 | |
| SCHEMBL4733229 | 0.87 | SLC6A4 (0.75) | HRH3SLC6A4SLC6A2CACNA1BCACNA1H | |
| SCHEMBL4916367 | 0.87 | SLC6A4 (1.00) | HRH3SLC6A4SLC6A2 | |
| SCHEMBL4910728 | 0.84 | HRH3 (0.72) | HRH3SLC6A4SLC6A2LTA4H | |
| Fumaric Acid SCHEMBL4922577 | 0.82 | SLC6A4 (0.65) | HRH3SLC6A4SLC6A2 | |
| Maleic Acid SCHEMBL4922562 | 0.82 | SLC6A4 (0.65) | HRH3SLC6A4SLC6A2 | |
| SCHEMBL4922567 | 0.81 | HRH3 (0.75) | HRH3SLC6A4SLC6A2 | |
| SCHEMBL17267470 | 0.80 | SLC7A5 (0.65) | HRH3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139564-A1 | SUBSTITUTED PHENYL PROPYL AMINES AS HISTAMINE H3 RECEPTOR AND SEROTONIN TRANSPORTER MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139564-A1 | SUBSTITUTED PHENYL PROPYL AMINES AS HISTAMINE H3 RECEPTOR AND SEROTONIN TRANSPORTER MODULATORS | HRH3, SLC6A4, HNMT | HRH3 1/4885SLC6A4 2/4885SLC6A2 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.