⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL9456290 | 0.97 | — | — | |
| SCHEMBL14128906 | 0.73 | — | — | |
| SCHEMBL17874638 | 0.73 | — | — | |
| SCHEMBL327059 | 0.71 | — | — | |
| SCHEMBL4201308 | 0.71 | — | — | |
| SCHEMBL8533882 | 0.71 | — | — | |
| SCHEMBL4206830 | 0.69 | — | — | |
| Potassium Ion SCHEMBL4206827 | 0.69 | — | — | |
| Ammonia Solution, Strong SCHEMBL8665452 | 0.69 | — | — | |
| SCHEMBL29993715 | 0.69 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11518685-B2 | Conversion of ammonium nitrate into useful products | SOUTHWEST RESEARCH INSTITUTE (US) | 2022-12-06 | — | — | US | claimed |
| CN-107098850-A | A kind of method for synthesizing the piperidones of 1 methyl, 3 nitro, 4 phenyl 2,6 2 | 西安近代化学研究所 | 2017-08-29 | — | — | CN | claimed |
| CN-101973907-B | Method for preparing N-nitroacetamide | XIAN MODERN CHEMISTRY RES INST | 2013-04-03 | — | — | CN | claimed |
| CN-1083447-C | Process for preparation of benzothiazolone compounds | ASTRA PHARMA PROD (SE) | 2002-04-24 | — | — | CN | claimed |
| CN-1248252-A | Preparation method of benzothiazolone compound | ASTRA PHARMA PROD (GB) | 2000-03-22 | — | — | CN | claimed |
| US-11702427-B2 | Substituted 2-pyridone tricyclic compounds, analogues thereof, and methods using same | ARBUTUS BIOPHARMA CORPORATION (CA) | 2023-07-18 | — | — | US | disclosed |
| US-11518685-B2 | Conversion of ammonium nitrate into useful products | SOUTHWEST RESEARCH INSTITUTE (US) | 2022-12-06 | — | — | US | disclosed |
| WO-2021155412-A1 | CONVERSION OF AMMONIUM NITRATE INTO USEFUL PRODUCTS | SOUTHWEST RESEARCH INSTITUTE (US) | 2021-08-05 | — | — | WO | disclosed |
| US-20210238047-A1 | Conversion of Ammonium Nitrate Into Useful Products | SOUTHWEST RESEARCH INSTITUTE | 2021-08-05 | — | — | US | disclosed |
| US-20210017186-A1 | SUBSTITUTED 2-PYRIDONE TRICYCLIC COMPOUNDS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2021-01-21 | — | — | US | disclosed |
| WO-2019177937-A1 | SUBSTITUTED 2-PYRIDONE TRICYCLIC COMPOUNDS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA, INC. (US) | 2019-09-19 | — | — | WO | disclosed |
| US-20130217683-A1 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USE THEREOF | MEMORY PHARMACEUTICALS CORPORATION (US) | 2013-08-22 | — | — | US | disclosed |
| EP-1074549-A2 | Tetrahydro-benzo(d)azepines and their use as antagonists at metabotropic glutamate receptors | F. HOFFMANN-LA ROCHE AG (CH) | 2001-02-07 | — | — | EP | disclosed |
| JP-2001004833-A | DYE-BASED POLARIZING FILM CONTAINING AZO COMPOUND | SUMITOMO CHEM CO LTD | 2001-01-12 | — | — | JP | disclosed |
| CN-1248252-A | Preparation method of benzothiazolone compound | ASTRA PHARMA PROD (GB) | 2000-03-22 | — | — | CN | disclosed |
| EP-0509769-B1 | Heterocyclic amides having HLE inhibiting activity | ZENECA LTD (GB) | 1996-09-11 | — | — | EP | disclosed |
| US-5521179-A | Heterocyclic amides | ZENECA LIMITED (GB) | 1996-05-28 | — | — | US | disclosed |
| EP-0509769-A2 | Heterocyclic amides having HLE inhibiting activity | ZENECA LIMITED (GB) | 1992-10-21 | — | — | EP | disclosed |
| CN-1062138-A | The synergy of HIV reverse transcriptase inhibitors | MERCK & CO INC (US) | 1992-06-24 | — | — | CN | disclosed |
| EP-0481802-A1 | Hydroxylated inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1992-04-22 | — | — | EP | disclosed |