Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 20/20 | 0.83 |
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.83 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4913211 | 0.91 | HRH3 (1.00) | SLC6A4HRH3SLC6A2 | |
| Trifluoroacetic Acid SCHEMBL4912805 | 0.91 | SLC6A4 (0.82) | SLC6A4HRH3SLC6A2 | |
| Trifluoroacetic Acid SCHEMBL4919853 | 0.91 | SLC6A4 (0.82) | SLC6A4HRH3SLC6A2 | |
| Trifluoroacetic Acid SCHEMBL4914866 | 0.91 | SLC6A4 (0.84) | SLC6A4HRH3SLC6A2 | |
| Trifluoroacetic Acid SCHEMBL4920932 | 0.90 | SLC6A4 (0.82) | SLC6A4HRH3SLC6A2 | |
| Trifluoroacetic Acid SCHEMBL4919605 | 0.90 | SLC6A4 (0.82) | SLC6A4HRH3SLC6A2 | |
| Trifluoroacetic Acid SCHEMBL4919843 | 0.88 | SLC6A4 (0.83) | SLC6A4HRH3SLC6A2 | |
| Trifluoroacetic Acid SCHEMBL4918146 | 0.87 | SLC6A4 (0.85) | SLC6A4HRH3SLC6A2 | |
| Trifluoroacetic Acid SCHEMBL4920719 | 0.86 | HRH3 (0.85) | SLC6A4HRH3SLC6A2 | |
| Trifluoroacetic Acid SCHEMBL4920832 | 0.85 | HRH3 (0.85) | SLC6A4HRH3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139564-A1 | SUBSTITUTED PHENYL PROPYL AMINES AS HISTAMINE H3 RECEPTOR AND SEROTONIN TRANSPORTER MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139564-A1 | SUBSTITUTED PHENYL PROPYL AMINES AS HISTAMINE H3 RECEPTOR AND SEROTONIN TRANSPORTER MODULATORS | HRH3, SLC6A4, HNMT | SLC6A4 2/4885HRH3 1/4885SLC6A2 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.