SCHEMBL4922033

SCHEMBL4922033

CNS(=O)(=O)CCS(=O)(=O)NC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10791888 0.87 NLRP3 (0.36)
SCHEMBL5720715 0.85 CA1 (0.30)
SCHEMBL7767282 0.85 PTGS1 (0.39)
SCHEMBL9934571 0.85
SCHEMBL4373286 0.83
SCHEMBL42331 0.83
SCHEMBL23963983 0.81
SCHEMBL7398952 0.81
SCHEMBL10854599 0.81
SCHEMBL105653 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8188269-B1 Functionalized compositions for improved immobilization LUMINEX CORPORATION (US) 2012-05-29 US disclosed
US-8188269-B1 Functionalized compositions for improved immobilization LUMINEX CORPORATION (US) 2012-05-29 US disclosed
US-20120123026-A1 FUNCTIONALIZED COMPOSITIONS FOR IMPROVED IMMOBILIZATION LUMINEX CORPORATION (US) 2012-05-17 US disclosed
US-7385053-B2 Functionalized compositions for improved immobilization LUMINEX CORPORATION (US) 2008-06-10 US disclosed
US-20080103061-A1 FUNCTIONALIZED COMPOSITIONS FOR IMPROVED IMMOBILIZATION LUMINEX CORPORATION (US) 2008-05-01 US disclosed
US-20080009512-A1 Tetrahydroquinolones and Aza-Analogues Thereof for Use as Dpp-IV Inhibitors in the Treatment of Diabetes ASTRAZENECA AB (SE) 2008-01-10 US disclosed
US-7241883-B2 Functionalized compositions for improved immobilization LUMINEX CORPORATION (US) 2007-07-10 US disclosed