Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F3 | P13726 | 11/20 | 0.96 |
| ▸ | DRD1 | P21728 | 9/20 | 0.96 |
| ▸ | DRD2 | P14416 | 6/20 | 0.96 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.96 |
| ▸ | DRD5 | P21918 | 3/20 | 0.96 |
| ▸ | DRD3 | P35462 | 3/20 | 0.96 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.96 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.96 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.96 |
| ▸ | DRD4 | P21917 | 2/20 | 0.96 |
| ▸ | LMNA | P02545 | 2/20 | 0.96 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.96 |
| ▸ | MEN1 | O00255 | 1/20 | 0.96 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.96 |
| ▸ | HTR1A | P08908 | 2/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | GAA | P10253 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydroberberine SCHEMBL30302597 | 0.98 | F3 (1.00) | F3DRD1DRD2CYP3A4DRD5 | |
| Tetrahydroberberine SCHEMBL14184002 | 0.98 | F3 (1.00) | F3DRD1DRD2CYP3A4DRD5 | |
| Tetrahydroberberine SCHEMBL2786492 | 0.98 | F3 (1.00) | F3DRD1DRD2CYP3A4DRD5 | |
| Tetrahydroberberine SCHEMBL232164 | 0.98 | F3 (1.00) | F3DRD1DRD2CYP3A4DRD5 | |
| Canadine SCHEMBL29365824 | 0.98 | F3 (1.00) | F3DRD1DRD2CYP3A4DRD5 | |
| Canadine SCHEMBL432394 | 0.98 | F3 (1.00) | F3DRD1DRD2CYP3A4DRD5 | |
| Tetrahydroberberine SCHEMBL30484836 | 0.98 | F3 (1.00) | F3DRD1DRD2CYP3A4DRD5 | |
| Tetrahydroberberine SCHEMBL3320124 | 0.97 | F3 (0.98) | F3DRD1DRD2CYP3A4DRD5 | |
| SCHEMBL2742547 | 0.89 | F3 (0.83) | F3DRD1DRD2CYP3A4DRD5 | |
| SCHEMBL2742464 | 0.89 | F3 (0.83) | F3DRD1DRD2CYP3A4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080124404-A1 | Hypolipidemic and/or hypocholesteremic compounds obtainable from the goldenseal plant | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-05-29 | — | — | US | disclosed |
| EP-0872903-B1 | Method for making hydrogen storage alloy powder and electrode comprising the alloy powder | SHINETSU CHEMICAL CO (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-6277519-B1 | QUENCHING AN ALLOY MELT; COMMINUTION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2001-08-21 | — | — | US | disclosed |
| EP-0872903-A1 | Method for making hydrogen storage alloy powder and electrode comprising the alloy powder | Shin-Etsu Chemical Co., Ltd. (JP) | 1998-10-21 | — | — | EP | disclosed |
| US-4758639-A | Process for production of vinyl polymer | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080124404-A1 | Hypolipidemic and/or hypocholesteremic compounds obtainable from the goldenseal plant | LIPA, HMGCR, LCAT | F3 529/4885DRD1 2571/4885DRD2 3145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.