Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.69 |
| ▸ | HPGD | P15428 | 9/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5013044 | 0.90 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL5012401 | 0.89 | ALDH1A1 (0.69) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL5015889 | 0.88 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL4053983 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL16222615 | 0.79 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL17344003 | 0.77 | KDM4E (0.88) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL17211719 | 0.77 | NPSR1 (0.79) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL1320500 | 0.76 | ALDH1A1 (0.66) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL16222482 | 0.75 | NPSR1 (0.85) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL4708582 | 0.74 | MEN1 (0.72) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9540389-B2 | Antimicrobial potentiators | MICROBIOTIX, INC. (US) | 2017-01-10 | — | — | US | disclosed |
| US-9540389-B2 | Antimicrobial potentiators | MICROBIOTIX, INC. (US) | 2017-01-10 | — | — | US | disclosed |
| US-20160075714-A1 | Antimicrobial Potentiators | MICROBIOTIX, INC. (US) | 2016-03-17 | — | — | US | disclosed |
| WO-2014179784-A2 | ANTIMICROBIAL POTENTIATORS | MICROBIOTIX, INC. (US) | 2014-11-06 | — | — | WO | disclosed |
| US-20080221096-A1 | Pyrido[3' ,2':4,5]Furo[3,2-d]Pyrimidine Derivatives | LABORATORIOS ALMIRALL, S.A. (ES) | 2008-09-11 | — | — | US | disclosed |
| US-20080207645-A1 | Pyridothienopyrimidine Derivatives | PAGES SANTACANA LUIS MIGUEL | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207645-A1 | Pyridothienopyrimidine Derivatives | PDE4A, PDE5A, PDE3B | ALDH1A1 438/4885KDM4E 1526/4885HPGD 25/4885 |
| US-20080221096-A1 | Pyrido[3' ,2':4,5]Furo[3,2-d]Pyrimidine Derivatives | NR1H2, CBR3, NR4A1 | ALDH1A1 2625/4885KDM4E 3618/4885HPGD 1978/4885 |
| US-20160075714-A1 | Antimicrobial Potentiators | NR1H2, ABCC5, NR1H3 | ALDH1A1 4200/4885KDM4E 3407/4885HPGD 1994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.