Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | HKDC1 | Q2TB90 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.49 |
| ▸ | HPGD | P15428 | 7/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4709157 | 0.86 | KDM4E (0.75) | KDM4EGLARXFP1HKDC1ALDH1A1 | |
| SCHEMBL4922646 | 0.84 | ALDH1A1 (0.56) | KDM4EGLAHKDC1ALDH1A1HPGD | |
| SCHEMBL5013112 | 0.82 | KDM4E (0.47) | KDM4EGLARXFP1HKDC1ALDH1A1 | |
| SCHEMBL4709055 | 0.74 | KDM4E (0.68) | KDM4EGLARXFP1HKDC1ALDH1A1 | |
| SCHEMBL4917120 | 0.74 | PDE4B (0.72) | KDM4EHKDC1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL4708892 | 0.74 | ALDH1A1 (0.68) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL4049238 | 0.71 | KDM4E (0.50) | KDM4ERXFP1HKDC1ALDH1A1HPGD | |
| SCHEMBL5054674 | 0.68 | POLB (0.54) | KDM4ERXFP1ALDH1A1HPGDKMT2A | |
| SCHEMBL4914020 | 0.68 | ALDH1A1 (0.58) | KDM4EGLARXFP1HKDC1ALDH1A1 | |
| SCHEMBL5013092 | 0.67 | KDM4E (0.55) | KDM4ERXFP1ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221096-A1 | Pyrido[3' ,2':4,5]Furo[3,2-d]Pyrimidine Derivatives | LABORATORIOS ALMIRALL, S.A. (ES) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221096-A1 | Pyrido[3' ,2':4,5]Furo[3,2-d]Pyrimidine Derivatives | NR1H2, CBR3, NR4A1 | KDM4E 3618/4885GLA 4801/4885RXFP1 943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.