SCHEMBL4923110

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5979572	0.92	MDM2 (0.73)	MDM2MCL1BCL2P4HTMRPA1
	SCHEMBL4933566	0.89	KMT2A (0.52)	MDM2MCL1BCL2MEN1KMT2A
	SCHEMBL5518559	0.87	MDM2 (0.48)	MDM2MCL1BCL2P4HTMMARS1
	SCHEMBL5524318	0.87	MDM2 (0.59)	MDM2MCL1BCL2P4HTMRPA1
	SCHEMBL14416517	0.86	MARS1 (0.47)	MDM2MCL1BCL2MARS1RPA1
	SCHEMBL4923151	0.84	MDM2 (0.45)	MDM2MCL1BCL2MEN1KMT2A
	SCHEMBL27668657	0.84	MDM2 (0.56)	MDM2MCL1BCL2P4HTMMARS1
	SCHEMBL5269383	0.83	MDM2 (0.57)	MDM2MCL1BCL2P4HTMMARS1
	SCHEMBL4927577	0.83	MARS1 (0.53)	MDM2MCL1BCL2MARS1RPA1
	SCHEMBL5163560	0.81	MARS1 (0.46)	MDM2MCL1BCL2MARS1RPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.