Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 11/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4925385 | 0.90 | PTGER1 (0.70) | PTGER1SMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL4924566 | 0.89 | SMN1; SMN2 (0.71) | PTGER1SMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL4914148 | 0.89 | PTGER1 (0.67) | PTGER1SMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL4916034 | 0.88 | PTGER1 (0.66) | PTGER1SMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL4915784 | 0.87 | PTGER1 (0.74) | PTGER1SMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL14034879 | 0.87 | PTGER1 (0.50) | PTGER1SMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL4927464 | 0.83 | PTGER1 (0.77) | PTGER1SMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL4926019 | 0.83 | PTGER1 (0.67) | PTGER1SMN1; SMN2ALDH1A1GAAPOLB | |
| SCHEMBL4923967 | 0.83 | PTGER1 (0.67) | PTGER1SMN1; SMN2ALDH1A1GAAPOLB | |
| SCHEMBL4771382 | 0.83 | PTGER1 (0.83) | PTGER1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287430-A1 | Furan Compounds Useful As Ep1 Receptor Antagonists | GLAXO GROUP LIMITED (GB) | 2008-11-20 | — | — | US | disclosed |
| US-20080287430-A1 | Furan Compounds Useful As Ep1 Receptor Antagonists | GLAXO GROUP LIMITED (GB) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287430-A1 | Furan Compounds Useful As Ep1 Receptor Antagonists | PTGER1, PTGER2, PTGER3 | PTGER1 1/4885SMN1; SMN2 3450/4885ALDH1A1 1015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.