Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1979309 | 0.85 | SLC22A6 (0.53) | SLC22A6MAPTPBRM1SMN1; SMN2TP53 | |
| SCHEMBL31744932 | 0.81 | SLC22A6 (0.50) | SLC22A6PBRM1SMN1; SMN2TP53NPSR1 | |
| SCHEMBL31744658 | 0.81 | SLC22A6 (0.50) | SLC22A6MAPTRAB9AHPGDPBRM1 | |
| SCHEMBL31744738 | 0.81 | SMN1; SMN2 (0.54) | SLC22A6MAPTRAB9ASMN1; SMN2TP53 | |
| SCHEMBL13429126 | 0.80 | KDM4E (0.50) | MAPTRAB9AHPGDSMN1; SMN2NPC1 | |
| SCHEMBL28007152 | 0.80 | SLC22A6 (0.51) | SLC22A6MAPTPBRM1NPSR1NR4A2 | |
| SCHEMBL31744565 | 0.78 | SLC22A6 (0.46) | SLC22A6MAPTRAB9APBRM1SMN1; SMN2 | |
| SCHEMBL27396972 | 0.78 | RHEB (0.51) | SLC22A6MAPTTP53NPSR1LMNA | |
| SCHEMBL4786081 | 0.77 | MAPT (0.64) | MAPTRAB9AHPGDSMN1; SMN2NPSR1 | |
| SCHEMBL4920498 | 0.77 | STING1 (0.49) | SLC22A6MAPTRAB9AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139484-A1 | 1(Beta-D-Glycopyranosyl)-3-Substituted Nitrogenous Heterocyclic Compound, Medicinal Composition Containing the Same, and Medicinal Use Thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-06-12 | — | — | US | disclosed |
| EP-1803729-A1 | 1-( -D-GLYCOPYRANOSYL)-3-SUBSTITUTED NITROGENOUS HETEROCYCLIC COMPOUND, MEDICINAL COMPOSITION CONTAINING THE SAME, AND MEDICINAL USE THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2007-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139484-A1 | 1(Beta-D-Glycopyranosyl)-3-Substituted Nitrogenous Heterocyclic Compound, Medicinal Composition Containing the Same, and Medicinal Use Thereof | SLC5A1, SLC5A2, UGGT1 | SLC22A6 397/4885MAPT 1185/4885RAB9A 2930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.