Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4019872 | 0.73 | KMT2A (0.37) | HTR2AKMT2AMEN1 | |
| SCHEMBL4024300 | 0.70 | KMT2A (0.39) | SLC18A3KMT2AMEN1 | |
| SCHEMBL4780182 | 0.70 | KMT2A (0.39) | SLC18A3KMT2AMEN1 | |
| SCHEMBL4025606 | 0.70 | KMT2A (0.39) | SLC18A3KMT2AMEN1 | |
| SCHEMBL3299615 | 0.68 | MAOB (0.53) | KMT2A | |
| SCHEMBL8782068 | 0.67 | HTR2A (0.45) | HTR2ASLC18A3KCNH2CPB1MGLL | |
| SCHEMBL18428493 | 0.63 | HTR2A (0.56) | HTR2ASLC18A3KCNH2CPB1MGLL | |
| SCHEMBL324342 | 0.63 | HTR2A (0.56) | HTR2ASLC18A3KCNH2CPB1MGLL | |
| SCHEMBL22491508 | 0.63 | CPB1 (0.49) | HTR2ACPB1MGLLKMT2AHSD11B1 | |
| SCHEMBL8788701 | 0.63 | MCL1 (0.45) | HTR2ASLC18A3CPB1MGLLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | claimed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | claimed |