Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 18/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.79 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5620237 | 0.98 | PTGER1 (0.82) | PTGER1CYP2C9MAOB | |
| SCHEMBL5620629 | 0.92 | PTGER1 (0.70) | PTGER1CYP2C9MAOB | |
| SCHEMBL5621256 | 0.92 | PTGER1 (0.69) | PTGER1CYP2C9MAOB | |
| SCHEMBL4923018 | 0.90 | PTGER1 (0.96) | PTGER1CYP2C9RXRARXRBRXRG | |
| SCHEMBL5620188 | 0.89 | PTGER1 (1.00) | PTGER1CYP2C9 | |
| SCHEMBL5621196 | 0.86 | PTGER1 (0.66) | PTGER1CYP2C9 | |
| SCHEMBL14499122 | 0.86 | PTGER1 (0.64) | PTGER1CYP2C9 | |
| SCHEMBL5620289 | 0.86 | PTGER1 (0.64) | PTGER1CYP2C9 | |
| SCHEMBL4159517 | 0.85 | PTGER1 (0.64) | PTGER1CYP2C9RXRARXRBRXRG | |
| SCHEMBL5620158 | 0.85 | PTGER1 (0.61) | PTGER1CYP2C9MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234335-A1 | Cyclohexene Compounds | GLAXO GROUP LIMITED (GB) | 2008-09-25 | — | — | US | disclosed |
| EP-1670764-A1 | CYCLOHEXENE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005037794-A1 | CYCLOHEXENE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2005-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234335-A1 | Cyclohexene Compounds | C1R, CYP1B1, CYP2C9 | PTGER1 377/4885CYP2C9 3/4885MAOB 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.