SCHEMBL4924149

SCHEMBL4924149

CCCCCCCC(=O)N(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTB4R2 Q9NPC1 1/20 0.63
LMNA P02545 2/20 0.58
NPC1 O15118 1/20 0.58
ALOX15 P16050 1/20 0.58
TSHR P16473 1/20 0.58
MAPK1 P28482 1/20 0.58
HSD17B10 Q99714 1/20 0.58
CNR2 P34972 1/20 0.56
ALOX5 P09917 3/20 0.55
EPHX2 P34913 1/20 0.54
BCHE P06276 1/20 0.54
ACHE P22303 1/20 0.54
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA4 P22748 1/20 0.52
HDAC3 O15379 1/20 0.50
HDAC1 Q13547 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29450616 1.00 LTB4R2 (0.63) LTB4R2LMNANPC1ALOX15TSHR
SCHEMBL28712083 1.00 LTB4R2 (0.63) LTB4R2LMNANPC1ALOX15TSHR
SCHEMBL4398063 0.98 LTB4R2 (0.64) LTB4R2LMNANPC1ALOX15TSHR
SCHEMBL28217434 0.94 LMNA (0.68) LTB4R2LMNANPC1ALOX15TSHR
SCHEMBL4330338 0.93 LTB4R2 (0.70) LTB4R2LMNANPC1ALOX15TSHR
SCHEMBL3455343 0.93 LTB4R2 (0.60) LTB4R2LMNANPC1ALOX15TSHR
SCHEMBL7238328 0.91 EPHX2 (0.60) LTB4R2LMNAALOX15HSD17B10CNR2
SCHEMBL27357692 0.90 LTB4R2 (0.56) LTB4R2LMNANPC1ALOX15TSHR
SCHEMBL4165489 0.90 CNR2 (0.56) LTB4R2LMNANPC1ALOX15TSHR
SCHEMBL4168772 0.90 CNR2 (0.56) LTB4R2LMNANPC1ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080081759-A1 PROCESS FOR THE PREPARATION OF GLYCOLALDEHYDE EASTMAN CHEMICAL COMPANY (US) 2008-04-03 US claimed
US-7301054-B1 Process for the preparation of glycolaldehyde EASTMAN CHEMICAL COMPANY (US) 2007-11-27 US claimed
US-4115204-A Separation of phenol-, cyclohexanone-, and cyclohexylbenzene-containing mixtures employing an N,N-disubstituted amide PHILLIPS PETROLEUM COMPANY (US) 1978-09-19 US claimed
US-20080081759-A1 PROCESS FOR THE PREPARATION OF GLYCOLALDEHYDE EASTMAN CHEMICAL COMPANY (US) 2008-04-03 US disclosed
US-7301054-B1 Process for the preparation of glycolaldehyde EASTMAN CHEMICAL COMPANY (US) 2007-11-27 US disclosed
US-4115204-A Separation of phenol-, cyclohexanone-, and cyclohexylbenzene-containing mixtures employing an N,N-disubstituted amide PHILLIPS PETROLEUM COMPANY (US) 1978-09-19 US disclosed