Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4165889 | 0.83 | CYP1A2 (0.57) | CYP1A2MAPTCA12CA1CA2 | |
| SCHEMBL4922618 | 0.80 | CYP1A2 (0.47) | CYP1A2MAPTCA12CA1CA2 | |
| SCHEMBL4922487 | 0.80 | CYP1A2 (0.47) | CYP1A2MAPTALDH1A1KDM4EGABRA2 | |
| SCHEMBL4923023 | 0.80 | CYP1A2 (0.39) | CYP1A2MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL5620136 | 0.79 | CYP1A2 (0.49) | CYP1A2MAPTCA12CA1CA2 | |
| SCHEMBL4159378 | 0.77 | CYP1A2 (0.50) | CYP1A2MAPTHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL4147291 | 0.77 | PTGER1 (0.49) | CYP1A2MAPTALDH1A1KDM4EGABRA2 | |
| SCHEMBL4926085 | 0.77 | CYP1A2 (0.47) | CYP1A2MAPTCA12CA1CA2 | |
| SCHEMBL4154407 | 0.77 | CYP1A2 (0.47) | CYP1A2MAPTCA12CA1CA2 | |
| SCHEMBL4154611 | 0.77 | CYP1A2 (0.47) | CYP1A2MAPTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234335-A1 | Cyclohexene Compounds | GLAXO GROUP LIMITED (GB) | 2008-09-25 | — | — | US | disclosed |
| EP-1670764-A1 | CYCLOHEXENE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005037794-A1 | CYCLOHEXENE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2005-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234335-A1 | Cyclohexene Compounds | C1R, CYP1B1, CYP2C9 | CYP1A2 51/4885MAPT 4485/4885CA12 2692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.