Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4924730 | 0.77 | CYP1A2 (0.59) | CYP1A2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4165889 | 0.74 | CYP1A2 (0.57) | CYP1A2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1743472 | 0.73 | ADORA1 (0.38) | MAPTADORA1ALDH1A1MEN1KMT2A | |
| SCHEMBL4924175 | 0.73 | CYP1A2 (0.44) | CYP1A2MAPTMEN1KMT2AHSP90AA1 | |
| SCHEMBL8202859 | 0.72 | ADORA1 (0.37) | MAPTADORA1SMN1; SMN2CASP3ALDH1A1 | |
| SCHEMBL17318442 | 0.72 | ADORA1 (0.37) | MAPTADORA1SMN1; SMN2CASP3ALDH1A1 | |
| SCHEMBL12592486 | 0.72 | ADORA1 (0.37) | MAPTADORA1SMN1; SMN2CASP3ALDH1A1 | |
| SCHEMBL1957632 | 0.71 | ADORA1 (0.38) | MAPTADORA1NPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL18584530 | 0.70 | ACHE (0.43) | — | |
| SCHEMBL4916416 | 0.69 | PTGER1 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234335-A1 | Cyclohexene Compounds | GLAXO GROUP LIMITED (GB) | 2008-09-25 | — | — | US | disclosed |
| EP-1670764-A1 | CYCLOHEXENE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005037794-A1 | CYCLOHEXENE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2005-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234335-A1 | Cyclohexene Compounds | C1R, CYP1B1, CYP2C9 | CYP1A2 51/4885MAPT 4485/4885ADORA1 176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.