SCHEMBL4924913

SCHEMBL4924913

CCOC(=O)c1ccc(N(c2ccccc2)c2ccc(-c3ccc(N(c4ccccc4)c4ccc(C(=O)OCC)cc4)cc3)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.60
KMT2A Q03164 1/20 0.60
SMN1; SMN2 Q16637 4/20 0.55
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
ESR1 P03372 1/20 0.54
CA7 P43166 1/20 0.54
CA9 Q16790 1/20 0.54
ESR2 Q92731 1/20 0.54
CA14 Q9ULX7 1/20 0.54
RAB9A P51151 3/20 0.54
NPC1 O15118 2/20 0.54
GAA P10253 1/20 0.54
CYP1A2 P05177 2/20 0.53
LMNA P02545 2/20 0.53
CYP3A4 P08684 1/20 0.53
MAOA P21397 1/20 0.53
ALDH1A1 P00352 2/20 0.52
RARA P10276 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9581699 0.97 MEN1 (0.60) MEN1KMT2ASMN1; SMN2CA12CA1
SCHEMBL21784421 0.95 KMT2A (0.61) MEN1KMT2ASMN1; SMN2CA12CA1
SCHEMBL9581324 0.90 TDP1 (0.52) MEN1KMT2ASMN1; SMN2CA12CA1
SCHEMBL12544707 0.89 CA12 (0.56) MEN1KMT2ASMN1; SMN2CA12CA1
SCHEMBL9581449 0.89 CA12 (0.56) MEN1KMT2ASMN1; SMN2CA12CA1
SCHEMBL24106782 0.88 MEN1 (0.70) MEN1KMT2ASMN1; SMN2CA12CA1
SCHEMBL570961 0.88 MEN1 (0.70) MEN1KMT2ASMN1; SMN2CA12CA1
Ethyl Benzoate SCHEMBL27862832 0.86 MEN1 (0.67) MEN1KMT2ASMN1; SMN2CA12CA1
Biphenyl SCHEMBL27937069 0.86 MEN1 (0.72) MEN1KMT2ASMN1; SMN2CA12CA1
SCHEMBL24979627 0.86 LMNA (0.60) MEN1KMT2ASMN1; SMN2ESR1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080054794-A1 Organic Electroluminescence Device, Image Display Apparatus and Lighting Apparatus Including the Same, Charge Transport Material and Charge Transport Layer Forming Ink Including the Same Fujiki, Michiya (JP) 2008-03-06 US disclosed