Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 9/20 | 0.69 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | QPCT | Q16769 | 1/20 | 0.51 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.51 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240554 | 0.81 | POLB (0.58) | CYP11B1CYP11B2POLBMAPTKDM4E | |
| SCHEMBL1806633 | 0.81 | CYP11B1 (1.00) | CYP11B1CYP11B2POLBMAPTKDM4E | |
| SCHEMBL30523908 | 0.81 | CYP11B1 (0.76) | CYP11B1CYP11B2POLBMAPTCYP19A1 | |
| SCHEMBL15179016 | 0.81 | CYP11B1 (0.76) | CYP11B1CYP11B2POLBMAPTCYP19A1 | |
| SCHEMBL30523909 | 0.81 | CYP11B1 (0.76) | CYP11B1CYP11B2POLBMAPTCYP19A1 | |
| SCHEMBL2729164 | 0.78 | CYP11B1 (1.00) | CYP11B1CYP11B2POLBMAPTKDM4E | |
| SCHEMBL11407205 | 0.78 | CYP11B1 (0.54) | CYP11B1CYP11B2POLBMAPTKDM4E | |
| SCHEMBL29908918 | 0.77 | POLB (0.81) | CYP11B1CYP11B2POLBMAPTKDM4E | |
| Iodide SCHEMBL1996528 | 0.76 | CYP11B1 (0.60) | CYP11B1CYP11B2POLBMAPTKDM4E | |
| SCHEMBL11409546 | 0.75 | CYP11B1 (0.49) | CYP11B1CYP11B2POLBKDM4ECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080267867-A1 | Metal Complexes of N-Heterocyclic Carbenes as Radiopharmaceuticals and Antibiotics | UNIVERSITY OF AKRON | 2008-10-30 | — | — | US | disclosed |
| EP-1660444-A4 | METAL COMPLEXES OF N-HETEROCYCLIC CARBENES AS RADIOPHARMACEUTICALS AND ANTIBIOTICS | UNIV AKRON (US) | 2007-12-26 | — | — | EP | disclosed |
| EP-1660444-A2 | METAL COMPLEXES OF N-HETEROCYCLIC CARBENES AS RADIOPHARMACEUTICALS AND ANTIBIOTICS | The University of Akron (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005023760-A2 | METAL COMPLEXES OF N-HETEROCYCLIC CARBENES AS RADIOPHARMACEUTICALS AND ANTIBIOTICS | THE UNIVERSITY OF AKRON (US) | 2005-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080267867-A1 | Metal Complexes of N-Heterocyclic Carbenes as Radiopharmaceuticals and Antibiotics | MKI67, C1S, CYC1 | CYP11B1 191/4885CYP11B2 393/4885POLB 1338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.