Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CYP11B1 | P15538 | 14/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 10/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | QPCT | Q16769 | 1/20 | 0.50 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.50 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4925205 | 0.81 | CYP11B1 (0.69) | POLBMAPTL3MBTL1KDM4EBRD4 | |
| SCHEMBL11407205 | 0.76 | CYP11B1 (0.54) | POLBMAPTKDM4ECYP11B1CYP11B2 | |
| SCHEMBL8050377 | 0.76 | CYP11B1 (0.65) | POLBMAPTL3MBTL1KDM4EBRD4 | |
| Bromide SCHEMBL10941970 | 0.75 | CYP11B1 (0.63) | POLBMAPTL3MBTL1KDM4EBRD4 | |
| SCHEMBL11412053 | 0.74 | KDM4E (0.50) | POLBMAPTL3MBTL1KDM4EBRD4 | |
| SCHEMBL11412333 | 0.74 | CYP11B1 (0.50) | POLBMAPTL3MBTL1KDM4EBRD4 | |
| SCHEMBL5595070 | 0.74 | BRD4 (1.00) | POLBMAPTL3MBTL1KDM4EBRD4 | |
| Hydrochloric Acid SCHEMBL11242521 | 0.73 | TBXAS1 (0.71) | POLBMAPTL3MBTL1KDM4EBRD4 | |
| SCHEMBL11243787 | 0.73 | TBXAS1 (0.58) | POLBMAPTL3MBTL1KDM4EBRD4 | |
| SCHEMBL11405750 | 0.73 | CYP19A1 (0.48) | LMNATDP1CYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339583-A | (Imidazolylmethyl)pyridine compounds as thromboxane synthetase inhibitors | PFIZER INC. (US) | 1982-07-13 | — | — | US | disclosed |
| EP-0029742-A1 | Imidazole derivatives, process for their preparation and pharmaceutical compositions thereof | Pfizer Limited (GB) | 1981-06-03 | — | — | EP | disclosed |
| US-4230714-A | Imidazole therapeutic agents | PFIZER INC. (US) | 1980-10-28 | — | — | US | disclosed |