SCHEMBL4925733

SCHEMBL4925733

CC(C)(F)OC(=O)/C=C\C(=O)OC(C)(C)F

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.41
KEAP1 Q14145 1/20 0.41
NFE2L2 Q16236 1/20 0.41
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4925738 0.91 HCAR2 (0.50) HCAR2KEAP1NFE2L2
SCHEMBL4925744 0.91 HCAR2 (0.50) HCAR2KEAP1NFE2L2
SCHEMBL9243018 0.79 HCAR2 (0.38) HCAR2KEAP1NFE2L2
SCHEMBL5457746 0.79
SCHEMBL10457339 0.79 HCAR2 (0.38) HCAR2KEAP1NFE2L2
SCHEMBL7778246 0.79 HCAR2 (0.38) HCAR2KEAP1NFE2L2
SCHEMBL1321101 0.77 HCAR2 (0.33) HCAR2KEAP1NFE2L2
SCHEMBL3400715 0.77 HCAR2 (0.38) HCAR2KEAP1NFE2L2
SCHEMBL5070247 0.77 HCAR2 (0.38) HCAR2KEAP1NFE2L2
SCHEMBL375029 0.77 HCAR2 (0.45) HCAR2KEAP1NFE2L2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080076054-A1 Toner, production method thereof, toner container, developer, image forming apparatus and process cartridge using the same RICOH COMPANY, LTD. (JP) 2008-03-27 US disclosed