SCHEMBL5070247

SCHEMBL5070247

O=C(/C=C/C(=O)OC(F)(F)F)OC(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.38
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3400712 1.00 HCAR2 (0.38) HCAR2KEAP1NFE2L2
SCHEMBL3400715 1.00 HCAR2 (0.38) HCAR2KEAP1NFE2L2
SCHEMBL27616968 0.89 HCAR2 (0.48) HCAR2KEAP1NFE2L2
SCHEMBL27927553 0.87 NFE2L2 (0.62) HCAR2KEAP1NFE2L2
SCHEMBL27880776 0.84
SCHEMBL8642499 0.84 KEAP1 (0.32) HCAR2KEAP1NFE2L2
SCHEMBL455400 0.84 KEAP1 (0.32) HCAR2KEAP1NFE2L2
SCHEMBL3515146 0.82 HCAR2 (0.57) HCAR2KEAP1NFE2L2
SCHEMBL28180704 0.82
SCHEMBL31143555 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7378032-B2 Coating composition for leather, coating method, and coated leather DAIKIN INDUSTRIES, LTD. (JP) 2008-05-27 US disclosed
US-20060150863-A1 Coating composition for leather, coating method, and coated leather DAIKIN INDUSTRIES, LTD. (JP) 2006-07-13 US disclosed
EP-1577400-A1 COATING COMPOSITION FOR LEATHER, COATING METHOD, AND COATED LEATHER Daikin Industries, Ltd. (JP) 2005-09-21 EP disclosed
US-6800679-B2 A BLEND COMPRISING A FLUOROPOLYMER AND A REPELLENT SELECTING FROM A PERFLUOROALKYL COMPOUND, A FLUORINE-CONTAINING SURFACTANT, A HALOCARBON OIL, A FLUOROSILICONE OIL OR A SILICONE OIL; WEATHER RESISTANCE DAIKIN INDUSTRIES, LTD. (JP) 2004-10-05 US disclosed
EP-0978537-B1 AQUEOUS DISPERSION COMPOSITION AND COATED ARTICLES DAIKIN IND LTD (JP) 2004-09-15 EP disclosed
US-6784239-B2 FOR USE IN CONCRETE, WOOD, CLOTH AND OTHER SUBSTRATES DAIKIN INDUSTRIES, LTD. (JP) 2004-08-31 US disclosed
US-20020165303-A1 Durable water repellent and coated articles WADA SUSUMU (JP) 2002-11-07 US disclosed
US-20020143099-A1 Durable water repellent and coated articles WADA SUSUMU (JP) 2002-10-03 US disclosed
US-6410626-B1 POLYSILOXANES AND FLUOROPOLYMER; PROTECTIVE COATING DAIKIN INDUSTRIES, LTD. (JP) 2002-06-25 US disclosed
EP-0978537-A1 AQUEOUS DISPERSION COMPOSITION AND COATED ARTICLES Daikin Industries, Ltd. (JP) 2000-02-09 EP disclosed
EP-0939105-A1 DURABLE WATER REPELLENT AND COATED ARTICLES DAIKIN INDUSTRIES, LTD. (JP) 1999-09-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060150863-A1 Coating composition for leather, coating method, and coated leather CUTA, LCAT, MLLT3 HCAR2 987/4885KEAP1 3096/4885NFE2L2 3500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.