Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4250076 | 0.87 | KDM4E (1.00) | KDM4EMAPK1MEN1KMT2AMCL1 | |
| SCHEMBL4924288 | 0.86 | KDM4E (1.00) | KDM4EMAPK1MEN1KMT2AMCL1 | |
| SCHEMBL29827612 | 0.84 | KDM4E (0.73) | KDM4EMAPK1MEN1KMT2AMCL1 | |
| SCHEMBL29827495 | 0.83 | KDM4E (0.71) | KDM4EMAPK1MEN1KMT2AMCL1 | |
| SCHEMBL29827374 | 0.82 | KDM4E (0.69) | KDM4EMAPK1MEN1KMT2AMCL1 | |
| SCHEMBL29827609 | 0.80 | KDM4E (0.66) | KDM4EMAPK1MEN1KMT2AMCL1 | |
| SCHEMBL30873710 | 0.80 | KDM4E (0.66) | KDM4EMAPK1MEN1KMT2AMCL1 | |
| SCHEMBL29827742 | 0.80 | KDM4E (0.66) | KDM4EMAPK1MEN1KMT2AMCL1 | |
| SCHEMBL29827366 | 0.79 | KDM4E (0.65) | KDM4EMAPK1MEN1KMT2AMCL1 | |
| SCHEMBL29827626 | 0.79 | KDM4E (0.65) | KDM4EMAPK1MEN1KMT2AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080039442-A1 | Compounds With Kv4 Ion Channel Activity | DEVGEN NV (BE) | 2008-02-14 | — | — | US | disclosed |
| US-20080039442-A1 | Compounds With Kv4 Ion Channel Activity | DEVGEN NV (BE) | 2008-02-14 | — | — | US | disclosed |
| US-20080039442-A1 | Compounds With Kv4 Ion Channel Activity | DEVGEN NV (BE) | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039442-A1 | Compounds With Kv4 Ion Channel Activity | KCNA4, HCN4, KCNN4 | KDM4E 618/4885MAPK1 2377/4885MEN1 2435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.