Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.69 |
| ▸ | ADORA1 | P30542 | 20/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 14/20 | 0.68 |
| ▸ | ADORA2B | P29275 | 14/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4919458 | 0.85 | ADORA2A (0.68) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL929014 | 0.82 | ADORA2A (1.00) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL929576 | 0.81 | ADORA2A (1.00) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL930816 | 0.80 | ADORA2A (0.82) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL928967 | 0.80 | ADORA2A (0.81) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL928981 | 0.79 | ADORA2A (1.00) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL4926241 | 0.79 | ADORA2A (0.72) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL4919469 | 0.79 | ADORA2A (0.72) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL928097 | 0.79 | ADORA2A (1.00) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL929166 | 0.78 | ADORA2A (0.74) | ADORA2AADORA1ADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080182860-A1 | Pyrimidine Compounds as Purine Receptor Antagonist | VERNALIS (R&D) LTD. (GB) | 2008-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182860-A1 | Pyrimidine Compounds as Purine Receptor Antagonist | ADORA3, P2RY10, ADORA2A | ADORA2A 3/4885ADORA1 4/4885ADORA3 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.