Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.72 |
| ▸ | KDM6B | O15054 | 1/20 | 0.72 |
| ▸ | TET3 | O43151 | 1/20 | 0.72 |
| ▸ | KDM4A | O75164 | 1/20 | 0.72 |
| ▸ | KDM4B | O94953 | 1/20 | 0.72 |
| ▸ | KDM5A | P29375 | 1/20 | 0.72 |
| ▸ | KDM5C | P41229 | 1/20 | 0.72 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.72 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.72 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.72 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.72 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20101080 | 1.00 | KDM4E (0.72) | KDM4EKDM6BTET3KDM4AKDM4B | |
| SCHEMBL15267189 | 0.90 | KDM4E (0.58) | KDM4EKDM6BTET3KDM4AKDM4B | |
| SCHEMBL20101083 | 0.87 | KDM4E (0.64) | KDM4EKDM6BTET3KDM4AKDM4B | |
| SCHEMBL18292348 | 0.85 | KMT2A (0.81) | KDM4EKDM6BTET3KDM4AKDM4B | |
| SCHEMBL29353093 | 0.84 | KDM4E (1.00) | KDM4EKDM6BTET3KDM4AKDM4B | |
| SCHEMBL17670545 | 0.84 | KDM4E (1.00) | KDM4EKDM6BTET3KDM4AKDM4B | |
| SCHEMBL18159120 | 0.84 | KDM4E (0.73) | KDM4EKDM6BTET3KDM4AKDM4B | |
| SCHEMBL20101032 | 0.84 | KDM4E (0.58) | KDM4EKDM6BTET3KDM4AKDM4B | |
| SCHEMBL20214000 | 0.84 | KDM4E (1.00) | KDM4EKDM6BTET3KDM4AKDM4B | |
| SCHEMBL29382353 | 0.84 | KDM4E (1.00) | KDM4EKDM6BTET3KDM4AKDM4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140171635-A1 | NOVEL HYDRAZONE-BASED AND OXIME-BASED FLUORESCENT AND CHROMOPHORIC/PRO-FLUORESCENT AND PRO-CHROMOPHORIC REAGENTS AND LINKERS | SOLULINK BIOSCIENCES, INC. (US) | 2014-06-19 | — | — | US | disclosed |
| US-8541555-B2 | Hydrazone-based and oxime-based fluorescent and chromophoric/pro-fluorescent and pro-chromophoric reagents and linkers | SOLULINK BIOSCIENCES, INC. (US) | 2013-09-24 | — | — | US | disclosed |
| US-20080221343-A1 | Labeled biomolecules of chromophore or the fluorophore incorporated into the linker between a reactive linking moiety and a biotin molecule; proteins, nucleic acids | AUDAX PRIVATE DEBT LLC, AS AGENT | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221343-A1 | Labeled biomolecules of chromophore or the fluorophore incorporated into the linker between a reactive linking moiety and a biotin molecule; proteins, nucleic acids | RRP12, MRPS22, HBG2 | KDM4E 4479/4885KDM6B 4156/4885TET3 2464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.