Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15362296 | 0.86 | TSHR (0.41) | PTPN1CES1MEN1KMT2ATSHR | |
| SCHEMBL7917024 | 0.79 | ESR1 (0.38) | MCOLN3POLBS1PR4ESR1GAA | |
| SCHEMBL21395985 | 0.77 | ESR1 (0.40) | HDAC6DOT1LS1PR4ESR1GAA | |
| SCHEMBL13569448 | 0.74 | ALDH1A1 (0.42) | ESR1PTPN1CES1MAPTMEN1 | |
| SCHEMBL28597260 | 0.74 | POLB (0.43) | MCOLN3POLBMEN1KMT2ALMNA | |
| SCHEMBL30962463 | 0.73 | CES1 (0.33) | HDAC6PTPN1CES1MEN1KMT2A | |
| SCHEMBL6120419 | 0.73 | ALDH1A1 (0.50) | POLBMEN1KMT2ALMNA | |
| SCHEMBL5798012 | 0.72 | S1PR4 (0.40) | HDAC6POLBS1PR4ESR1GAA | |
| SCHEMBL11742715 | 0.72 | MYC (0.45) | POLBMAPTMEN1KMT2ALMNA | |
| SCHEMBL22336611 | 0.71 | ALDH1A1 (0.48) | HDAC6MCOLN3CES1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249318-A1 | Process for phenylacetic acid derivatives | ACEMOGLU MURAT | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249318-A1 | Process for phenylacetic acid derivatives | ALDH7A1, CYP4F11, CYP2A6 | HDAC6 1103/4885DOT1L 2265/4885MCOLN3 4362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.